Mast cells play an important role in host defense against various pathogens, but their role in
viral infection has not been clarified in detail. dsRNA, synthesized by various types of …

The characteristics, importance, and molecular requirements for interactions between mast
cells (MCs) and CD8 + T cells have not been elucidated. Here, we demonstrated that MCs …

CD37 is a leukocyte-specific protein belonging to the tetraspanin superfamily. Previously
thought to be predominantly a B cell molecule, CD37 is shown in this study to regulate T cell …

CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53, CD63,
CD81, and CD82. Many of these molecules are expressed on leukocytes and have been …

Mast cells (MCs), which are well known for their effector functions in T H 2-skewed allergic
and also autoimmune inflammation, have become increasingly acknowledged for their role in …

Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses
against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral …

Sepsis remains a global clinical problem. By using the mouse cecal ligation and puncture
model of sepsis, here we identify an important aspect of mast cell (MC)-dependent, innate …

CD63 is a member of the tetraspanin superfamily that constitutes a main component of the
lysosomal membrane. In mice, two CD63 gene loci are present, with only one of these two …

ATP-gated ion channel P2X receptors are expressed on the surface of most immune cells
and can trigger multiple cellular responses, such as membrane permeabilization, cytokine …

Axl, a prototypic member of the transmembrane tyrosine kinase receptor family, is known to
regulate innate immunity. In this study, we show that Axl expression is induced by IFN-α …