… Heterogeneity was assessed using Cochrane's Q, a statistic based on the chi-square test
with corresponding Z- and p-values. As this test is known to have low power, the chi-square …

To establish the effectiveness of interventions for the acute and long‐term management of
anaphylaxis, seven databases were searched for systematic reviews, randomized controlled …

Anaphylaxis is a clinical emergency, and all healthcare professionals should be familiar with
its recognition and acute and ongoing management. These guidelines have been prepared …

… 1 z-score, FEV 1 /FVC, age of onset/diagnosis, number of exacerbations in preceding 12
months, ACT z… z-score (regression coefficient 0.76, p<0.001) and FEV 1 z-score (0.11, p=0.036). …

AMP-activated protein kinase (AMPK) is an important energy sensor that may be critical in
regulating renal lipid accumulation. To evaluate the role of AMPK in mediating renal lipid …

Background Autism spectrum disorders (ASDs) are caused by both genetic and environmental
factors. Mitochondria act to connect genes and environment by regulating gene-encoded …

Background Children born to atopic parents are at increased risk of sensitization to
environmental allergens. Objective We sought to demonstrate proof of concept for oral …

Pyruvate dehydrogenase deficiency is a major cause of primary lactic acidosis and neurological
dysfunction in infancy and early childhood. Most cases are caused by mutations in the X…

Background Stratification by eosinophil and neutrophil counts increases our understanding
of asthma and helps target therapy, but there is room for improvement in our accuracy in …

The aim of this study was to evaluate muscle magnetic resonance imaging findings in
patients with congenital muscular dystrophy and Ullrich phenotype. Fifteen children with …