Safety and pharmacokinetics of nintedanib and pirfenidone in idiopathic pulmonary fibrosis

…, T Fujimoto, K Okazaki, Y Tadayasu… - European …, 2015 - Eur Respiratory Soc
A randomised, double-blind, phase II, dose escalation trial was conducted to assess the
safety, tolerability and pharmacokinetics of the tyrosine kinase inhibitor nintedanib, alone and …

Population pharmacokinetics of tamsulosin hydrochloride in paediatric patients with neuropathic and non‐neuropathic bladder

…, S Tatami, N Yamamura, Y Tadayasu… - British journal of …, 2010 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT Tamsulosin is available on prescription
as a modified release capsule in the US (Flomax®), and in most European countries for …

Population pharmacokinetic/pharmacodynamic analysis of the DPP-4 inhibitor linagliptin in Japanese patients with type 2 diabetes mellitus

Y Tadayasu, A Sarashina, Y Tsuda… - … of Pharmacy & …, 2013 - journals.library.ualberta.ca
[Objectives] Linagliptin is a novel, highly selective and long acting DPP-4 inhibitor for the
treatment of type 2 diabetes mellitus (T2DM). Linagliptin exhibits non-linear pharmacokinetics (…

Phase I study of nintedanib in Japanese patients with advanced hepatocellular carcinoma and liver impairment

…, R Sugimoto, K Muro, I Saito, Y Tadayasu… - Cancer …, 2016 - Wiley Online Library
This phase I, dose‐escalation study evaluated the safety, preliminary efficacy and
pharmacokinetics of nintedanib, a triple angiokinase inhibitor, in Japanese patients with advanced …

Efficacy and safety of the long-acting β2-agonist olodaterol over 4 weeks in Japanese patients with chronic obstructive pulmonary disease

…, A Takizawa, T Izumoto, Y Tadayasu… - … Journal of Chronic …, 2015 - Taylor & Francis
Background Olodaterol is a novel long-acting β 2 -agonist with proven ≥24-hour duration of
action in preclinical and clinical studies. Objective This randomized, double-blind, placebo-…

[HTML][HTML] Pharmacokinetics and safety of tiotropium+ olodaterol 5 μg/5 μg fixed-dose combination in Chinese patients with COPD

Z Wang, Y Tadayasu, N Hu, S Shu, C Hu… - Pulmonary Pharmacology …, 2020 - Elsevier
Background Chronic obstructive pulmonary disease (COPD) is one of the major causes of
morbidity and mortality worldwide and in China. For patients with more severe symptoms, …

LATE-BREAKING ABSTRACT: Safety, pharmacokinetics and pharmacodynamics of BI 1060469, a novel oral CRTH2 antagonist

…, E Benediktus, C Schepers, JM Kim, Y Tadayasu… - 2016 - Eur Respiratory Soc
Introduction: BI 1060469, a novel oral antagonist of the chemo-attractant receptor-homologous
molecule on T-helper-2 cells (CRTH2), targets airway inflammation in asthma by …

[PDF][PDF] … Nagata, Makoto Nasu, Yusuke Kaida, Yosuke Nakayama, Yuka Kurokawa, Nao Nakamura, Ryo Shibata, Takuma Hazama, Takahiro Tsukimura, Tadayasu …

K Fukami - Nephrol Dial Transplant, 2021 - pdfs.semanticscholar.org
10 Terryn W et al.[28] Belgium 2008 180 DBS test p. Trp236Arg (1) 1/180 (0.56) 11 Andrade
J et al.[4] Canada 2008 499 Plasma N/A (0) 0/499 (0) 12 Fujii H et al.[29] Japan 2009 635 …

[HTML][HTML] Analysis of the complete genome sequences of Clostridium perfringens strains harbouring the binary enterotoxin BEC gene and comparative genomics of …

K Ueda, K Kawahara, N Kimoto, Y Yamaguchi… - BMC genomics, 2022 - Springer
Background BEC-producing Clostridium perfringens is a causative agent of foodborne
gastroenteritis. It was first reported in 2014, and since then, several isolates have been identified …

FROM THE MUSEUM

T Kotsimbos, ME Laucho-Contreras, F Polverino… - Eur Respiratory Soc
… , Masashi Bando, Shinji Abe, Yoshiro Mochizuki, Kingo Chida, Matthias Klüglich, Tsuyoshi
Fujimoto, Kotaro Okazaki, Yusuke Tadayasu, Wataru Sakamoto and Yukihiko Sugiyama …