[HTML][HTML] Epigenetics: a potential mechanism involved in the pathogenesis of various adverse consequences of obstructive sleep apnea

YC Chen, PY Hsu, CC Hsiao, MC Lin - International journal of molecular …, 2019 - mdpi.com
Epigenetics is defined as the heritable phenotypic changes which do not involve alterations
in the DNA sequence, including histone modifications, non-coding RNAs, and DNA …

Long‐acting beta2‐agonists versus long‐acting muscarinic antagonists in patients with stable COPD: a systematic review and meta‐analysis of randomized controlled …

WC Chen, CH Huang, CC Sheu, IW Chong… - …, 2017 - Wiley Online Library
Several long‐acting bronchodilators have been developed and are widely used as first‐line
treatment in patients with stable chronic obstructive pulmonary disease ( COPD ). However, …

[HTML][HTML] Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts

YC Chen, CC Hsiao, CJ Chen, CH Chin, SF Liu… - BMC medical …, 2010 - Springer
Background To investigate whether the toll-like receptor 2 polymorphisms could influence
susceptibility to pulmonary TB, its phenotypes, and blood lymphocyte subsets. Methods A total …

Mortality and vertebral fracture risk associated with long-term oral steroid use in patients with chronic obstructive pulmonary disease: a systemic review and meta …

…, KA Chu, JR Tsai, CH Lee, YC Chen - Chronic Respiratory …, 2019 - journals.sagepub.com
Short-term oral steroid use may improve lung function and respiratory symptoms in patients
with stable chronic obstructive pulmonary disease (COPD). However, long-term oral steroid (…

[HTML][HTML] Mortality risk factors in patients with Acinetobacter baumannii ventilator-associated pneumonia

HC Chang, YC Chen, MC Lin, SF Liu, YH Chung… - Journal of the Formosan …, 2011 - Elsevier
BACKGROUND/PURPOSE: Ventilator-associated pneumonia (VAP) caused by Acinetobacter
baumannii has contributed to high mortality rate, prolonged stays in the intensive care unit…

Diagnostic and prognostic values of pleural fluid procalcitonin in parapneumonic pleural effusions

MC Lin, YC Chen, JT Wu, YC Ko, CC Wang - Chest, 2009 - Elsevier
Background The role of procalcitonin in parapneumonic pleural effusion (PPPE) as a diagnostic
and prognostic biomarker of the outcome has not been examined before. Methods From …

Inspiratory muscle training in bronchiectasis patients: a prospective randomized controlled study

…, KT Huang, PW Chang, YC Chen… - Clinical …, 2011 - journals.sagepub.com
Objective: To investigate the efficacy and feasibility of home-based inspiratory muscle
training in patients with bronchiectasis. Design: A prospective, single-blind, randomized, …

[HTML][HTML] Leukocyte mitochondrial DNA copy number is associated with chronic obstructive pulmonary disease

SF Liu, HC Kuo, CW Tseng, HT Huang, YC Chen… - PloS one, 2015 - journals.plos.org
Background Oxidative stress is known to be involved in the pathogenesis of chronic
obstructive pulmonary disease (COPD). Evidence suggests that leukocytes mitochondria DNA (…

Prognostic values of serum IP-10 and IL-17 in patients with pulmonary tuberculosis

YC Chen, CH Chin, SF Liu, CC Wu, CC Tsen… - Disease …, 2011 - content.iospress.com
Objective: To identify patients at high risk of relapse after anti-tuberculosis (TB) therapy or
with poor long-term outcomes. Methods: Fifty-one patients with pulmonary TB: 7 were …

Whole Genome DNA Methylation Analysis of Obstructive Sleep Apnea: IL1R2,NPR2, AR, SP140 Methylation and Clinical Phenotype

YC Chen, TW Chen, MC Su, CJ Chen, KD Chen… - Sleep, 2016 - academic.oup.com
Study Objectives We hypothesized that DNA methylation patterns may contribute to disease
severity or the development of hypertension and excessive daytime sleepiness (EDS) in …