The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells

M Yamaya, Y Shimotai, Y Hatachi, NL Kalonji… - Pulmonary …, 2015 - Elsevier
Background Serine proteases act through the proteolytic cleavage of the hemagglutinin (HA)
of influenza viruses for the entry of influenza virus into cells, resulting in infection. However, …

Association of diffuse, random pulmonary metastases, including miliary metastases, with epidermal growth factor receptor mutations in lung adenocarcinoma

…, K Masago, T Kubo, Y Sakamori, YH Kim, Y Hatachi… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Although the association of multiple pulmonary metastases, and particularly
miliary metastases, with response to gefitinib treatment in patients with nonsmall cell lung …

Clarithromycin inhibits type a seasonal influenza virus infection in human airway epithelial cells

M Yamaya, K Shinya, Y Hatachi, H Kubo… - … of Pharmacology and …, 2010 - ASPET
Human influenza viruses attach to sialic acid with an α2,6linkage (SAα2,6Gal) on the airway
epithelial cells, and the entry of the viruses into the cells and uncoating of the viruses …

[HTML][HTML] Neutrophil-to-lymphocyte ratio as a predictive or prognostic factor for gastric cancer treated with nivolumab: a multicenter retrospective study

T Ogata, H Satake, M Ogata, Y Hatachi, K Inoue… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Methods This was a multicenter, retrospective study of patients with AGC treated with
nivolumab from June 2017 to December 2017. The NLRs were calculated before the first cycle (…

Macrolide antibiotics inhibit respiratory syncytial virus infection in human airway epithelial cells

M Asada, M Yoshida, T Suzuki, Y Hatachi, T Sasaki… - Antiviral research, 2009 - Elsevier
To examine the effects of macrolide antibiotics on RS virus infection in airways, human
tracheal epithelial cells were pre-treated with bafilomycin A 1 and clarithromycin, and infected …

Effect of vascular endothelial growth factor polymorphisms on survival in advanced‐stage non‐small‐cell lung cancer

K Masago, S Fujita, YH Kim, Y Hatachi… - Cancer …, 2009 - Wiley Online Library
Polymorphisms have been identified in the vascular endothelial growth factor (VEGF) gene
that may affect VEGF production. We hypothesized that such polymorphisms may correlate …

Inhibitory effects of carbocisteine on type A seasonal influenza virus infection in human airway epithelial cells

…, H Nishimura, K Shinya, Y Hatachi… - … of Physiology-Lung …, 2010 - journals.physiology.org
Type A human seasonal influenza (FluA) virus infection causes exacerbations of bronchial
asthma and chronic obstructive pulmonary disease (COPD). l-carbocisteine, a mucolytic agent…

Effectiveness of crizotinib for inflammatory myofibroblastic tumor with ALK mutation

M Ogata, Y Hatachi, T Ogata, H Satake, Y Imai… - Internal …, 2019 - jstage.jst.go.jp
Inflammatory myofibroblastic tumor (IMT), a rare sarcoma, is primarily treated via resection of
the mass. However, in cases of recurrence or unresectable tumors, no standard care exists. …

[HTML][HTML] Hyperprogressive disease in the irradiation field after a single dose of nivolumab for gastric cancer: a case report

T Ogata, H Satake, M Ogata, Y Hatachi… - Case Reports in …, 2018 - karger.com
Following the ATTRACTION-2 study, nivolumab was approved for advanced gastric cancer
in Japan. However, pseudoprogression and hyperprogressive disease have been reported …

[HTML][HTML] Genetic polymorphisms in the endothelial nitric oxide synthase gene correlate with overall survival in advanced non-small-cell lung cancer patients treated …

S Fujita, K Masago, Y Hatachi, A Fukuhara, A Hata… - BMC medical …, 2010 - Springer
Background Nitric oxide (NO) is a free radical that is involved in carcinogenesis. Endothelial
NO, synthesized from L-arginine by endothelial NO synthase (eNOS), inhibits apoptosis and …