Mitochondrial DNA (mtDNA) editing paves the way for disease modeling of mitochondrial
genetic disorders in cell lines and animals and also for the treatment of these diseases in the …

Aberrantly enhanced vascular endothelial growth factor (VEGF) gene expression is associated
with increased tumor growth and metastatic spread of solid malignancies, including …

Severe acute respiratory syndrome coronavirus nonstructural protein 13 (SCV nsP13), a
superfamily 1 helicase, plays a central role in viral RNA replication through the unwinding of …

Osteoblast differentiation is a critical step in the maintenance of bone homeostasis.
Osteoblast differentiation is generally maintained by growth hormone (GH) and various other …

Unlike CRISPR-Cas9 nucleases, which yield DNA double-strand breaks (DSBs), Cas9
nickases (nCas9s), which are created by replacing key catalytic amino-acid residues in one of …

Targeted cancer therapy with natural compounds is more effective than nontargeted therapy.
Nobiletin is a flavonoid derived from citrus peel that has anticancer activity. Cluster of …

Non-small-cell lung cancer (NSCLC) is the most common lung cancer subtype and
accounts for more than 80% of all lung cancer cases. Epidermal growth factor receptor (EGFR) …

Tannic acid ( TA ), a naturally occurring polyphenol, is a potent anti‐oxidant with anti‐proliferative
effects on multiple cancers. However, its ability to modulate gene‐specific expression …

… ; Young Mok Yang and Jong Hwan Park also contributed to designing the experiments and
the analysis of data; Dong Young … with corresponding author Young Mok Yang. All authors …

Background Thoroughbred horses are the most expensive domestic animals, and their
running ability and knowledge about their muscle-related diseases are important in animal …