[HTML][HTML] Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

YP De Visser, FJ Walther, EH Laghmani, H Boersma… - Respiratory …, 2009 - Springer
Background Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe
pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in …

Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension

S Umar, YP de Visser, P Steendijk… - American Journal …, 2009 - journals.physiology.org
Pulmonary arterial hypertension (PAH) is a chronic lung disease that leads to right ventricular
(RV) hypertrophy (RVH), remodeling, and failure. We tested treatment with bone marrow-…

Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopulmonary disease in rats with neonatal hyperoxia-induced lung injury

…, YP De Visser, L De Vries… - … of Physiology-Lung …, 2013 - journals.physiology.org
de Visserde Visserde Visser YP , Walther FJ , Laghmani EH , van der Laarse A ,
Wagenaar GT. Apelin attenuates hyperoxic lung and heart injury in neonatal rats. Am J Respir Crit …

[HTML][HTML] 17α‐Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor α

ACA Cleuren, IK van der Linden, YP de Visser… - Journal of Thrombosis …, 2010 - Elsevier
Background: Oral estrogen use is associated with changes in plasma levels of many coagulation
proteins. Objective: To gain more insight into the underlying mechanism of estrogen‐…

Phosphodiesterase-4 inhibition attenuates pulmonary inflammation in neonatal lung injury

YP de Visser, FJ Walther, EH Laghmani… - European …, 2008 - Eur Respiratory Soc
Phosphodiesterase-4 (PDE4) inhibitors may offer novel therapeutic strategies in respiratory
diseases, including asthma and chronic obstructive pulmonary disease. Therefore, selective …

Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats

YP de Visser, FJ Walther… - … of Physiology-Lung …, 2012 - journals.physiology.org
Phosphodiesterase (PDE) 4 inhibitors are potent anti-inflammatory drugs with antihypertensive
properties, and their therapeutic role in bronchopulmonary dysplasia (BPD) is still …

The effect of 'two hit'neonatal and young‐adult stress on dopaminergic modulation of prepulse inhibition and dopamine receptor density

KHC Choy, YP De Visser… - British journal of …, 2009 - Wiley Online Library
Background and purpose: A combination of early neurodevelopmental insult(s) and young‐adult
stress exposure may be involved in the development of schizophrenia. We studied …

Apelin attenuates hyperoxic lung and heart injury in neonatal rats

YP Visser, FJ Walther, EH Laghmani… - American journal of …, 2010 - atsjournals.org
de Visserde Visserde Visser YP, Walther FJ, Laghmani EH, van der Laarse A, Wagenaar
GT. Apelin attenuates pulmonary inflammation and fibrin deposition in neonatal hyperoxic …

Ambrisentan reduces pulmonary arterial hypertension but does not stimulate alveolar and vascular development in neonatal rats with hyperoxic lung injury

…, EH Laghmani, YP de Visser… - … of Physiology-Lung …, 2013 - journals.physiology.org
de Visserde Visserde Visser YP, Walther FJ, Laghmani EH, van der Laarse A, Wagenaar
GT. Apelin attenuates hyperoxic lung and heart injury in neonatal rats. Am J Respir Crit Care …

Apelin Attenuates Pulmonary Inflammation and Fibrin Deposition in Neonatal Hyperoxic Lung Injury.

YP De Visser, FJ Walther, EH Laghmani… - A97. BEST IN …, 2009 - atsjournals.org
Rationale: To study the role of apelin as a therapeutic strategy to prevent bronchopulmonary
dysplasia (BPD) in preterm infants with respiratory distress syndrome. Methods: Neonatal …