[HTML][HTML] Targeting PI3K in cancer: mechanisms and advances in clinical trials
Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling
is one of the most important intracellular pathways, which can be considered as a master …
is one of the most important intracellular pathways, which can be considered as a master …
[HTML][HTML] Mesenchymal stem cells: a new trend for cell therapy
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in the
clinic for approximately 10 years. From animal models to clinical trials, MSCs have afforded …
clinic for approximately 10 years. From animal models to clinical trials, MSCs have afforded …
[HTML][HTML] Role of pyroptosis in inflammation and cancer
X Wei, F Xie, X Zhou, Y Wu, H Yan, T Liu… - Cellular & molecular …, 2022 - nature.com
Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of cellular …
continuous cell expansion until the cytomembrane ruptures, resulting in the release of cellular …
[HTML][HTML] A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a respiratory disease
called coronavirus disease 2019 (COVID-19), the spread of which has led to a pandemic. …
called coronavirus disease 2019 (COVID-19), the spread of which has led to a pandemic. …
YOLOv6: A single-stage object detection framework for industrial applications
For years, the YOLO series has been the de facto industry-level standard for efficient object
detection. The YOLO community has prospered overwhelmingly to enrich its use in a …
detection. The YOLO community has prospered overwhelmingly to enrich its use in a …
Fully convolutional one-stage 3d object detection on lidar range images
We present a simple yet effective fully convolutional one-stage 3D object detector for LiDAR
point clouds of autonomous driving scenes, termed FCOS-LiDAR. Unlike the dominant …
point clouds of autonomous driving scenes, termed FCOS-LiDAR. Unlike the dominant …
[HTML][HTML] Expanded encyclopaedias of DNA elements in the human and mouse genomes
…, J Huey, DE Dickel, V Snetkova, X Wei, X Wang… - Nature, 2020 - nature.com
The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate these …
govern the timing, magnitude, and cellular context of their production. To better delineate these …
Antibody neutralization and escape by HIV-1
X Wei, JM Decker, S Wang, H Hui, JC Kappes, X Wu… - Nature, 2003 - nature.com
Neutralizing antibodies (Nab) are a principal component of an effective human immune
response to many pathogens, yet their role in HIV-1 infection is unclear 1 , 2 , 3 , 4 , 5 , 6 . To gain …
response to many pathogens, yet their role in HIV-1 infection is unclear 1 , 2 , 3 , 4 , 5 , 6 . To gain …
Twins: Revisiting the design of spatial attention in vision transformers
Very recently, a variety of vision transformer architectures for dense prediction tasks have
been proposed and they show that the design of spatial attention is critical to their success in …
been proposed and they show that the design of spatial attention is critical to their success in …
Genome-wide association studies of 14 agronomic traits in rice landraces
X Huang, X Wei, T Sang, Q Zhao, Q Feng, Y Zhao… - Nature …, 2010 - nature.com
Uncovering the genetic basis of agronomic traits in crop landraces that have adapted to
various agro-climatic conditions is important to world food security. Here we have identified ∼…
various agro-climatic conditions is important to world food security. Here we have identified ∼…