User profiles for William Leeds

William B. Leeds

Senior Data Scientist, wellio
Verified email at getwellio.com
Cited by 253

Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma

…, JN Kline, AH Mansur, BE Louie, WM Leeds… - Journal of allergy and …, 2013 - Elsevier
Background Bronchial thermoplasty (BT) has previously been shown to improve asthma
control out to 2 years in patients with severe persistent asthma. Objective We sought to assess …

A randomised trial of lung sealant versus medical therapy for advanced emphysema

…, DK Hogarth, K Kolandaivelu, W Leeds… - European …, 2015 - Eur Respiratory Soc
Uncontrolled pilot studies demonstrated promising results of endoscopic lung volume
reduction using emphysematous lung sealant (ELS) in patients with advanced, upper lobe …

Telehealth services to improve nonadherence: a placebo-controlled study

…, FN Puno, D Cook, G Doolittle, W Leeds - … Journal & e-Health, 2006 - liebertpub.com
The objective of this study was to test whether a telehealth intervention could improve the
compliance with continuous positive airway pressure (CPAP) by patients with sleep apnea. …

Biologic lung volume reduction in advanced upper lobe emphysema: phase 2 results

…, M Dransfield, M Gotfried, W Leeds… - American Journal of …, 2009 - atsjournals.org
Rationale: Biologic lung volume reduction (BioLVR) is a new endobronchial treatment for
advanced emphysema that reduces lung volume through tissue remodeling. Objectives: …

Lower risk and higher yield for thoracentesis when performed by experienced operators

…, PD Mayo, MR Pratter, RJ Santarelli, WM Leeds… - Chest, 1993 - journal.chestnet.org
RESULTS Between Oct 11, 1990, and March 20, 1992, 50 consecutive thoracenteses that
met criteria were performed. Thirty-five thoracenteses were performed by fellows (21 by one …

Assessing first-order emulator inference for physical parameters in nonlinear mechanistic models

MB Hooten, WB Leeds, J Fiechter, CK Wikle - Journal of Agricultural …, 2011 - Springer
We present an approach for estimating physical parameters in nonlinear models that relies
on an approximation to the mechanistic model itself for computational efficiency. The …

Modern statistical methods in oceanography: A hierarchical perspective

CK Wikle, RF Milliff, R Herbei, WB Leeds - Statistical Science, 2013 - JSTOR
Processes in ocean physics, air-sea interaction and ocean biogeochemistry span enormous
ranges in spatial and temporal scales, that is, from molecular to planetary and from seconds …

Emulator-assisted reduced-rank ecological data assimilation for nonlinear multivariate dynamical spatio-temporal processes

WB Leeds, CK Wikle, J Fiechter - Statistical Methodology, 2014 - Elsevier
As ecological data sets increase in spatial and temporal extent with the advent of new
remote sensing platforms and long-term monitoring networks, there is increasing interest in …

Simulation of future climate under changing temporal covariance structures

WB Leeds, EJ Moyer, ML Stein - Advances in Statistical …, 2015 - ascmo.copernicus.org
A growing body of evidence indicates that anthropogenic greenhouse gases are changing
Earth's climate, and that those changes may involve not only changes in climatic means but …

Fatal poisoning with sodium fluoroacetate: report of a case

…, AV McDowell, WG Leeds - Journal of the American …, 1955 - jamanetwork.com
Extensive chemical research carried out in recent years has produced a rodenticide, sodium
fluoroacetate, which has been found to be very effective and extremely toxic. Sodium …