Treatment strategies for the right heart in pulmonary hypertension
…, N Saouti, WJ Van Der Laarse… - Cardiovascular …, 2017 - academic.oup.com
The function of the right ventricle (RV) determines the prognosis of patients with pulmonary
hypertension. While much progress has been made in the treatment of pulmonary …
hypertension. While much progress has been made in the treatment of pulmonary …
Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
While the heart regenerates poorly in mammals, efficient heart regeneration occurs in
zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes …
zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes …
[HTML][HTML] Rapid quantification of myocardial fibrosis: a new macro-based automated analysis
Background Fibrosis is associated with various cardiac pathologies and dysfunction.
Current quantification methods are time-consuming and laborious. We describe a semi-automated …
Current quantification methods are time-consuming and laborious. We describe a semi-automated …
Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency
…, WJ van der Laarse, FS de Man… - Pulmonary …, 2015 - journals.sagepub.com
In patients with idiopathic pulmonary arterial hypertension (iPAH), iron deficiency is common
and has been associated with reduced exercise capacity and worse survival. Previous …
and has been associated with reduced exercise capacity and worse survival. Previous …
Maximal oxygen uptake is proportional to muscle fiber oxidative capacity, from chronic heart failure patients to professional cyclists
…, RT Jaspers, WJ van der Laarse - Journal of applied …, 2016 - journals.physiology.org
… Bekedam MA, van Beek-Harmsen BJ, Boonstra A, van Mechelen W, Visser FC, van der
Laarse WJ. Maximum rate of oxygen consumption related to succinate dehydrogenase activity in …
Laarse WJ. Maximum rate of oxygen consumption related to succinate dehydrogenase activity in …
Iron deficiency in systemic sclerosis patients with and without pulmonary hypertension
…, IJ Lanser, FS de Man, WJ van der Laarse… - …, 2014 - academic.oup.com
Objectives. SSc-associated pulmonary hypertension (SSc-PH) has a worse prognosis compared
with SSc without PH (SSc-nonPH). Iron deficiency (ID) was previously associated with …
with SSc without PH (SSc-nonPH). Iron deficiency (ID) was previously associated with …
Right ventricular failure in idiopathic pulmonary arterial hypertension is associated with inefficient myocardial oxygen utilization
…, N Westerhof, WJ van der Laarse… - Circulation: Heart …, 2011 - Am Heart Assoc
… Willem J. van der Laarse … Wong YY, Handoko ML, Mouchaers KTB, De Man FS, Vonk
Noordegraaf A, Van Der Laarse WJ . Reduced mechanical efficiency of rat papillary muscle related …
Noordegraaf A, Van Der Laarse WJ . Reduced mechanical efficiency of rat papillary muscle related …
Critical determinants of combined sprint and endurance performance: an integrative analysis from muscle fiber to the human body
Optimizing physical performance is a major goal in current physiology. However, basic
understanding of combining high sprint and endurance performance is currently lacking. This …
understanding of combining high sprint and endurance performance is currently lacking. This …
[HTML][HTML] Oxygenation threshold derived from near-infrared spectroscopy: reliability and its relationship with the first ventilatory threshold
…, A de Haan, JJ de Koning, WJ van der Laarse… - PloS one, 2016 - journals.plos.org
Background Near-infrared spectroscopy (NIRS) measurements of oxygenation reflect O 2
delivery and utilization in exercising muscle and may improve detection of a critical exercise …
delivery and utilization in exercising muscle and may improve detection of a critical exercise …
Diaphragm muscle fiber weakness in pulmonary hypertension
…, GJM Stienen, WJ van der Laarse… - American journal of …, 2011 - atsjournals.org
… Willem J. van der Laarse … Man FS, Happe CM, Schalij I, Musters RJ, Westerhof N, Postmus
PE, Paulus WJ, van der Laarse WJ, Vonk-Noordegraaf A. Opposite effects of training in rats …
PE, Paulus WJ, van der Laarse WJ, Vonk-Noordegraaf A. Opposite effects of training in rats …