Antituberculosis drug‐induced hepatotoxicity: concise up‐to‐date review

…, RE Aarnoutse, WCM De Lange… - Journal of …, 2008 - Wiley Online Library
The cornerstone of tuberculosis management is a 6‐month course of isoniazid, rifampicin,
pyrazinamide and ethambutol. Compliance is crucial for curing tuberculosis. Adverse effects …

Potential antimicrobial agents for the treatment of multidrug-resistant tuberculosis

…, B Wilffert, R van Altena, WCM de Lange… - European …, 2014 - Eur Respiratory Soc
Treatment of multidrug-resistant (MDR) tuberculosis (TB) is challenging because of the high
toxicity of second-line drugs and the longer treatment duration than for drug-susceptible TB …

Evaluation of Carbapenems for Treatment of Multi- and Extensively Drug-Resistant Mycobacterium tuberculosis

…, OW Akkerman, WCM de Lange… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Multi- and extensively drug-resistant tuberculosis (M/XDR-TB) has become an increasing
threat not only in countries where the TB burden is high but also in affluent regions, due to …

[HTML][HTML] Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients

…, WJ Koh, J Lancaster, C Lange, WCM de Lange… - 2012 - journals.plos.org
Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic,
expensive, and has generally poor outcomes. We undertook an individual patient data meta-…

Clinical relevance of non-tuberculous mycobacteria isolated in the Nijmegen-Arnhem region, The Netherlands

J van Ingen, SA Bendien, WCM de Lange, W Hoefsloot… - Thorax, 2009 - thorax.bmj.com
Background: The frequency of clinical isolation of non-tuberculous mycobacteria (NTM) in the
Netherlands is increasing, but its clinical relevance is often uncertain. Objective: To assess …

Clinical Relevance of Mycobacterium szulgai in The Netherlands

J van Ingen, MJ Boeree, WCM de Lange… - Clinical Infectious …, 2008 - academic.oup.com
Background . The clinical relevance of Mycobacterium szulgai isolates is unknown, and
available literature focuses on case reports of M. szulgai disease. We assessed the clinical …

Clinical relevance of Mycobacterium malmoense isolation in The Netherlands

…, J van Ingen, WCM de Lange… - European …, 2009 - Eur Respiratory Soc
Uncertainty exists about the clinical relevance of Mycobacterium malmoense isolation,
especially in pulmonary samples. We therefore determined clinical relevance, treatment and …

Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients

…, D van Soolingen, WCM de Lange… - European …, 2013 - Eur Respiratory Soc
The use of linezolid for the treatment of multidrug-resistant tuberculosis is limited by dose-
and time-dependent toxicity. Recently, we reported a case of pharmacokinetic drug–drug …

Pharmacokinetics of bedaquiline in cerebrospinal fluid and serum in multidrug-resistant tuberculous meningitis

…, OFF Odish, MS Bolhuis, WCM de Lange… - Clinical Infectious …, 2016 - academic.oup.com
TO THE EDITOR—Despite considerable advances in the diagnosis and treatment of
tuberculosis, central nervous system tuberculosis is still a devastating and often lifethreatening …

Incorporating therapeutic drug monitoring into the World Health Organization hierarchy of tuberculosis diagnostics

…, OW Akkerman, WCM de Lange… - European …, 2016 - Eur Respiratory Soc
Tuberculosis (TB), once considered as a disease of the past generally afflicting poor people,
still claims 1.5 million lives annually [1]. Although 86% of patients with drug susceptible TB …