User profiles for Werner Seeger

Werner Seeger

Professor, Justus Liebig University Giessen; MPI-HLR; CPI; UGMLC; DZL; ILH
Verified email at ugmlc.de
Cited by 87276

Clinical classification of pulmonary hypertension

…, N Galič, LJ Rubin, D Langleben, W Seeger… - Journal of the American …, 2004 - jacc.org
In 1998, during the Second World Symposium on Pulmonary Hypertension (PH) held in
Evian, France, a clinical classification of PH was proposed. The aim of the Evian classification …

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

…, N Weissmann, A Gunther, D Walmrath, W Seeger… - The Lancet, 2002 - thelancet.com
Background Lung fibrosis can be complicated by pulmonary hypertension, limiting exercise
tolerance and life expectancy. Furthermore, vasodilators might cause deterioration in gas …

[HTML][HTML] Inhaled iloprost for severe pulmonary hypertension

…, H Siedentop, W Seeger - … England Journal of …, 2002 - Mass Medical Soc
Background Uncontrolled studies suggested that aerosolized iloprost, a stable analogue of
prostacyclin, causes selective pulmonary vasodilatation and improves hemodynamics and …

Pulmonary hypertension in chronic lung diseases

W Seeger, Y Adir, JA Barberā, H Champion… - Journal of the American …, 2013 - jacc.org
Chronic obstructive lung disease (COPD) and diffuse parenchymal lung diseases (DPLD),
including idiopathic pulmonary fibrosis (IPF) and sarcoidosis, are associated with a high …

[HTML][HTML] Reversal of experimental pulmonary hypertension by PDGF inhibition

…, YJ Lai, N Weissmann, W Seeger… - The Journal of …, 2005 - Am Soc Clin Investig
Progression of pulmonary hypertension is associated with increased proliferation and migration
of pulmonary vascular smooth muscle cells. PDGF is a potent mitogen and involved in …

Updated treatment algorithm of pulmonary arterial hypertension

…, IR Preston, LJ Rubin, J Sandoval, W Seeger… - Journal of the American …, 2013 - jacc.org
The demands on a pulmonary arterial hypertension (PAH) treatment algorithm are multiple
and in some ways conflicting. The treatment algorithm usually includes different types of …

Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea: impact of continuous positive airway pressure therapy

…, H Olschewski, K Mayer, W Seeger… - American journal of …, 2000 - atsjournals.org
Obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity and
mortality. Free oxygen radicals have been implicated in the pathogenesis of cardiovascular …

Pulmonary hypertension due to left heart diseases

…, M Semigran, G Simonneau, A Wells, W Seeger - Journal of the American …, 2013 - jacc.org
Pulmonary hypertension (PH), a common complication of left heart diseases (LHD), negatively
impacts symptoms, exercise capacity, and outcome. Although the true prevalence of PH-…

Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension

…, RT Schermuly, N Weissmann, W Seeger… - Annals of internal …, 2002 - acpjournals.org
Background: Inhalation of the stable prostacyclin analogue iloprost is being studied for
treatment of pulmonary hypertension. The selective phosphodiesterase-5 inhibitor sildenafil has …

[HTML][HTML] Functional Wnt signaling is increased in idiopathic pulmonary fibrosis

…, N Balsara, EM Pfaff, M Kramer, I Chrobak, W Seeger… - PloS one, 2008 - journals.plos.org
Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease, characterized by
distorted lung architecture and loss of respiratory function. Alveolar epithelial cell injury and …