Infection of mucosal epithelium by papillomaviruses is responsible for the induction of
genital and oral warts and plays a critical role in the development of human cervical and …

Background The amount of dietary fat required for optimal bioavailability of carotenoids in
plant matrices is not clearly defined. Objective The objective was to quantify the appearance of …

Respiratory syncytial virus (RSV) is the leading cause of viral bronchiolitis and pneumonia
in infants and children. Currently, palivizumab is the only approved monoclonal antibody (mAb…

Objective To characterise activation of the type I interferon (IFN) pathway in patients with
systemic lupus erythematosus (SLE), dermatomyositis (DM), polymyositis (PM), rheumatoid …

Background Hypertensive disorders of pregnancy (HDP) are associated with increased risks
for cardiovascular disease later in life. The HDP incidence is commonly assessed using …

Single equimolar doses (0.5 mumol/kg body wt) of lutein and/or beta-carotene in true
solution in oil were given to eight adult subjects and 13 blood samples were taken during the …

Vitamin A deficiency (VAD) affects over 250 million people worldwide and is one of the most
prevalent nutritional deficiencies in developing countries, resulting in significant socio-…

Objective To evaluate the safety and tolerability of multiple intravenous (IV) doses of
sifalimumab in adults with moderate‐to‐severe systemic lupus erythematosus (SLE). Methods In …

Background Type I interferons (IFNs) appear to play a central role in disease pathogenesis
in systemic lupus erythematosus (SLE), making them potential therapeutic targets. Methods …

Nuclear receptors are a family of transcription factors with structurally conserved ligand
binding domains that regulate their activity. Despite intensive efforts to identify ligands, most …