Until now detection and numeration of circulating tumor cells (CTCs) were essentially used
as a prognostic factor in cancer progression. To extend the role of these kinds of analysis, it …

Today, drug combinations are frequently used in the treatment of cancer to increase therapeutic
efficacy. Currently used clinical protocols for cancer combination therapies are mainly …

Octext. —A mutation in theBRCA1gene may confer substantial risk for breast and/or ovarian
cancer. However, knowledge regarding all possible mutations and the relationship between …

Lung cancer is a leading cause of cancer death and late diagnosis is one of the most important
reasons for the high mortality rate. Circulating microRNAs (miRNAs) represent stable and …

The characterization of circulating tumor cells (CTCs) could substantially improve the
management of cancer patients. However, their study is still a matter of debate, often due to …

Purpose: The identification of new molecular markers for the early detection of colorectal
cancer has become an important objective. We compared the sensitivity and specificity of free …

Objectives Urine cell-free (UCF) DNA has recently been proposed as a potential marker for
early bladder cancer diagnosis. It is known that normal apoptotic cells produce highly …

Lung cancer is often diagnosed at an advanced stage, with subsequently poor prognosis.
There are no biomarkers available to facilitate early diagnosis or to discriminate between …

Background Non-invasive early detection of lung cancer could reduce the number of
patients diagnosed with advanced disease, which is associated with a poor prognosis. We …

Background Despite the great advances in the understanding of programmed cell death, little
attention has been paid to the sequence of the events that characterise it. In particular, the …