An inverse relationship exists between striated muscle fiber size and its oxidative capacity.
This relationship implies that muscle fibers, which are triggered to simultaneously increase …

The function of the right ventricle (RV) determines the prognosis of patients with pulmonary
hypertension. While much progress has been made in the treatment of pulmonary …

Background— Exercise training in pulmonary arterial hypertension (PH) is a promising
adjunct to medical treatment. However, it is still unclear whether training is beneficial for all PH …

We determined the physiological effects of exercise training on exercise capacity and
quadriceps muscle function in patients with idiopathic pulmonary arterial hypertension (iPAH). In …

The aims of this study were to assess the prevalence of iron deficiency in idiopathic pulmonary
arterial hypertension (IPAH) and investigate whether oral iron supplementation has …

While the heart regenerates poorly in mammals, efficient heart regeneration occurs in
zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes …

Background Fibrosis is associated with various cardiac pathologies and dysfunction.
Current quantification methods are time-consuming and laborious. We describe a semi-automated …

… AL, Lee-de Groot MBE, Gwilt JW, van der Laarse WJ. 1999. … Elzinga G, van der Laarse WJ.
1988. Oxygen consumption of … Lee-de Groot MBE, des Tombe AL, van der Laarse WJ. 1998…

Pulmonary arterial hypertension (PAH) still cannot be cured, warranting the search for novel
treatments. Fasudil (a Rho kinase inhibitor) was compared with bosentan (an endothelin …

… We thank Frank Oosterveer, Iris van der Mark, Martha Wagenaar, Colette ter Heerdt, Pia Trip,
Sylvia Bogaards, John Wharton, Patrick Jak, Jerica Sinkeldam, Rita Visser, … van der Laarse …