User profiles for Valentin Lozanov

valentin lozanov

Medical University of Sofia
Verified email at medfac.acad.bg
Cited by 1222

[PDF][PDF] Specific inhibition of insect α-amylases: yellow meal worm α-amylase in complex with the Amaranth α-amylase inhibitor at 2.0 Å resolution

PJB Pereira, V Lozanov, A Patthy, R Huber, W Bode… - Structure, 1999 - cell.com
Background: α-Amylases constitute a family of enzymes that catalyze the hydrolysis of α-D-(1,4)-glucan
linkages in starch and related polysaccharides. The Amaranth α-amylase …

Simultaneous analysis of amino acid and biogenic polyamines by high-performance liquid chromatography after pre-column derivatization with N-(9 …

V Lozanov, S Petrov, V Mitev - Journal of Chromatography A, 2004 - Elsevier
A high-performance liquid chromatography method for the simultaneous analysis of amino
acids and biogenic polyamines, using a new procedure for pre-column derivatization of …

Antiepileptogenic and neuroprotective effects of losartan in kainate model of temporal lobe epilepsy

…, N Lazarov, L Kortenska, R Mitreva, V Lozanov… - Pharmacology …, 2014 - Elsevier
Recently, we have shown that the blockade of AT 1 receptor might be useful as an adjuvant
treatment strategy for the prevention of oxidative stress and neurotoxicity caused by status …

[PDF][PDF] Antitumor activity of Bulgarian herb Tribulus terrestris L. on human breast cancer cells

V Lozanov, T Markov, S Bozhanov… - Journal of BioScience …, 2013 - academia.edu
Medicinal plants have been intensively studied as a source of antitumor compounds. Due to
the beneficial climate conditions Bulgarian herbs have high pharmacological potential. …

Prophylactic treatment with melatonin after status epilepticus: Effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal …

…, S Moyanova, L Kortenska, R Mitreva, V Lozanov… - Epilepsy & Behavior, 2013 - Elsevier
Melatonin is a potent antioxidant which showed anticonvulsant activities both in experimental
and clinical studies. In the present study, we examined the effect of melatonin treatment (…

Long-term treatment with losartan attenuates seizure activity and neuronal damage without affecting behavioral changes in a model of co-morbid hypertension and …

…, N Lazarov, L Kortenska, R Mitreva, V Lozanov… - Cellular and molecular …, 2016 - Springer
Over the last 10 years, accumulated experimental and clinical evidence has supported the
idea that AT 1 receptor subtype is involved in epilepsy. Recently, we have shown that the …

Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and …

…, R Mitreva, D Popov, P Markova, V Lozanov… - Epilepsy & Behavior, 2014 - Elsevier
Melatonin is involved in the control of circadian and seasonal rhythmicity, possesses potent
antioxidant activity, and exerts a neuroprotective and anticonvulsant effect. Spontaneously …

[HTML][HTML] Solution structure of the major α-amylase inhibitor of the crop plant amaranth

…, R Han, X Gu, S Liang, X Wang, F Li, V Lozanov… - Journal of Biological …, 1999 - ASBMB
α-Amylase inhibitor (AAI), a 32-residue miniprotein from the Mexican crop plant amaranth (Amaranthus
hypochondriacus), is the smallest known α-amylase inhibitor and is specific for …

HPLC‐UV and LC–MS Analyses of Acylquinic Acids in Geigeria alata (DC) Oliv. & Hiern. and their Contribution to Antioxidant and Antimicrobial Capacity

…, H Najdenski, S Ruseva, V Lozanov… - Phytochemical …, 2017 - Wiley Online Library
Introduction Geigeria alata is a traditional plant used in Sudanese folk medicine for treatment
of diabetes, cough, epilepsy and intestinal complaints. Objective To analyze phenolic acids …

[HTML][HTML] Aggregation induced nucleic acids recognition by homodimeric asymmetric monomethyne cyanine fluorochromes in mesenchymal stem cells

…, T Stoyanova, VV Lozanova, VS Lozanov… - International Journal of …, 2023 - Elsevier
In the light of recent retrovirus pandemics, the issue of discovering new and diverse RNA-specific
fluorochromes for research and diagnostics became of acute importance. The great …