[HTML][HTML] A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling

VR Ramirez-Carrozzi, D Braas, DM Bhatt, CS Cheng… - Cell, 2009 - cell.com
We describe a broad mechanistic framework for the transcriptional induction of mammalian
primary response genes by Toll-like receptors and other stimuli. One major class of primary …

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

V Ramirez-Carrozzi, A Sambandam, E Luis, Z Lin… - Nature …, 2011 - nature.com
Interleukin 17C (IL-17C) is a member of the IL-17 family that is selectively induced in epithelia
by bacterial challenge and inflammatory stimuli. Here we show that IL-17C functioned in a …

Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response

VR Ramirez-Carrozzi, AA Nazarian, CC Li… - Genes & …, 2006 - genesdev.cshlp.org
… Mi-2β, the analysis was expanded to include other LPS-induced genes, including genes
described previously and genes identified in microarray experiments (VR Ramirez-Carrozzi and …

The interleukin‐17 cytokine family: critical players in host defence and inflammatory diseases

R Pappu, V RamirezCarrozzi, A Sambandam - Immunology, 2011 - Wiley Online Library
The interleukin‐17 (IL‐17) cytokines, IL‐17A to IL‐17F, are emerging as critical players in
host defence responses and inflammatory diseases. Substantial data support the role of these …

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1

…, D Yan, AA Khan, A Abbas, V Ramirez-Carrozzi… - Nature …, 2013 - nature.com
Type 2 innate lymphoid cells (ILC2 cells) participate in host defense against helminth parasites
and in allergic inflammation. Given their functional relatedness to type 2 helper T cells (T …

[HTML][HTML] TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers

X Yu, R Pappu, V Ramirez-Carrozzi, N Ota… - Mucosal …, 2014 - nature.com
Immune responses at mucosal barriers are regulated by innate type 2 lymphoid cells (ILC2s)
that elaborate effector cytokines interleukins 5 and 13 (IL5 and IL13). IL25 and IL33 are key …

The IL-17 family cytokines in immunity and disease

R Pappu, V Ramirez-Carrozzi, N Ota… - Journal of clinical …, 2010 - Springer
Introduction Accumulating evidence suggests that the interleukin (IL)-17 cytokines are major
players in the immune response to foreign pathogens. In addition, the pathogeneses of a …

[HTML][HTML] Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IκBζ

H Kayama, VR Ramirez-Carrozzi, M Yamamoto… - Journal of biological …, 2008 - ASBMB
Toll-like receptors trigger the induction of primary response genes via MyD88-mediated
activation of NF-κB and other transcription factors. These factors then act in concert with primary …

Endogenously expressed IL-13Rα2 attenuates IL-13–mediated responses but does not activate signaling in human lung fibroblasts

…, J Jackman, J Bevers, V Ramirez-Carrozzi… - The Journal of …, 2014 - journals.aai.org
IL-13 can bind to two distinct receptors: a heterodimer of IL-13Rα1/IL-4Rα and IL-13Rα2.
Whereas IL-13Rα1/IL-4Rα engagement by IL-13 leads to the activation of STAT6, the molecular …

Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma

…, J Wang, J Bevers III, V Ramirez-Carrozzi… - Science translational …, 2022 - science.org
Exacerbations of symptoms represent an unmet need for people with asthma. Bacterial
dysbiosis and opportunistic bacterial infections have been observed in, and may contribute to, …