The effect of intermittent hypoxia (IHx) on blood hemoglobin concentration ([Hb]) and the
underlying mechanisms were studied in rats exposed to 10% O 2 , 1 h/day, for up to 5 wk. IHx …

Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for arterial thrombosis,
which is associated with high cardiovascular morbidity and mortality. To investigate the …

Dyspnea consists of various uncomfortable respiratory sensations. It is believed that hypoxia
causes dyspnea, but whether hypoxia is a direct dyspnogenic factor remains uncertain. We …

It is not clear whether blood hemoglobin concentration ([Hb]) increases with an increase in
the exposure period of intermittent hypoxia (IHx) and reaches a constant level. Furthermore, it …

The purpose of this study was to compare the pathological findings of injury induced by
chronic hypoperfusion and by chronic hypoxia in rat brain. Adult male Wistar rats were divided …

The prevalence and natural history of cor pulmonale in COPD are not yet clear. Factors that
are known to contribute to the development of pulmonary hypertension in COPD include …

Introduction and Materials and Methods: In Japan, deaths due to malignant neoplasms
reached 320,000 per year in 2005; most of these were due to lung cancer and totaled over …

The effects of hypoxia on pulmonary arterial pressure (PAP) and on development of pulmonary
edema, ascertained by changes in lung water and pulmonary vascular permeability were …

Object The fold plication method is a newoperative procedure for lung volume reduction
surgery whereby the target area is obliterated by plicating the folded tissue using a knifeless …

We have previously shown that intermittent hypoxia (IHx, 10% O 2 , 60 min/day) leads to an
increase in the splenic α2-adrenoceptor response and results in a splenic contraction-…