Striated muscle is a tissue in which gene expression is influenced to a large extent by
mechanical signals. This includes the regulation of gene expression-associated muscle fiber …

Urea is an endogenous metabolite, known to enhance stratum corneum hydration. Yet,
topical urea anecdotally also improves permeability barrier function, and it appears to exhibit …

Photoprotection of human skin by means of sunscreens or daily skin‐care products is traditionally
centered around the prevention of acute (eg sunburn) and chronic (eg skin cancer and …

We have isolated and sequenced the gene and the cDNA coding for the human cardiac β-myosin
heavy chain (designated MYH7). The gene is 22,883 bp long. The 1935 amino acids …

Background. Pre-exposure prophylaxis (PrEP) is an effective prevention tool for people at
substantial risk of acquiring human immunodeficiency virus (HIV). To monitor the current state …

Infrared A radiation ( IRA ) from solar sunlight contributes to photoaging of human skin, eg
by upregulating MMP ‐1 expression in dermal fibroblasts, indicating the need for …

Introduction and Objectives: In recent years there has been an increasing interest in the use
of nutritional supplements to benefit human skin. Molecular evidence substantiating such …

Importance At least 500 000 people in the US experience homelessness nightly. More than
30% of people experiencing homelessness also have a substance use disorder. Involuntary …

Using electrical stimulation to control force generation and limb immobilization to alter the
degree of stretch, we have studied the role of mechanical activity in inducing hypertrophy and …

The ‘matrikine’ concept claims that processing of the precursors for collagen results in the
formation of peptides such as KTTKS which in turn augments extracellular matrix (ECM) …