[HTML][HTML] Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study
…, C Clarenbach, C Garzoni, TK Geiser… - European respiratory …, 2021 - Eur Respiratory Soc
Background The infectious coronavirus disease 2019 (COVID-19) pandemic is an ongoing
global healthcare challenge. Up to one-third of hospitalised patients develop severe …
global healthcare challenge. Up to one-third of hospitalised patients develop severe …
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
…, SE Dahlen, K Dyson, U Frey, T Geiser… - European …, 2015 - Eur Respiratory Soc
U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical
companies and six patient organisations with the objective of improving the understanding …
companies and six patient organisations with the objective of improving the understanding …
[HTML][HTML] Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes.
M Loetscher, T Geiser, T O'Reilly, R Zwahlen… - Journal of Biological …, 1994 - Elsevier
Several chemotactic agonists including interleukin-8 (IL-8) and related cytokines have been
shown to activate and attract leukocytes via seven-transmembrane domain, GTP-binding …
shown to activate and attract leukocytes via seven-transmembrane domain, GTP-binding …
Neutrophil activation by monomeric interleukin-8
…, BD Sykes, CM Kay, B Dewald, T Geiser… - Science, 1994 - science.org
Interleukin-8 (IL-8), a pro-inflammatory protein, has been shown by nuclear magnetic
resonance (NMR) and x-ray techniques to exist as a homodimer. An IL-8 analog was chemically …
resonance (NMR) and x-ray techniques to exist as a homodimer. An IL-8 analog was chemically …
[HTML][HTML] A lung-on-a-chip array with an integrated bio-inspired respiration mechanism
…, M Felder, Y Mermoud, RA Schmid, T Geiser… - Lab on a Chip, 2015 - pubs.rsc.org
We report a lung-on-a-chip array that mimics the pulmonary parenchymal environment,
including the thin alveolar barrier and the three-dimensional cyclic strain induced by breathing …
including the thin alveolar barrier and the three-dimensional cyclic strain induced by breathing …
Monocyte chemotactic protein 3 is a most effective basophil-and eosinophil-activating chemokine.
CA Dahinden, T Geiser, T Brunner… - The Journal of …, 1994 - rupress.org
CC chemokines constitute a novel class of cytokines that attract and activate monocytes and
lymphocytes, as well as basophil and eosinophil leukocytes, with distinct target cell profiles, …
lymphocytes, as well as basophil and eosinophil leukocytes, with distinct target cell profiles, …
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
…, G Galffy, H Gallart, T Garret, T Geiser… - Journal of Allergy and …, 2017 - Elsevier
Background Asthma is a heterogeneous disease in which there is a differential response to
asthma treatments. This heterogeneity needs to be evaluated so that a personalized …
asthma treatments. This heterogeneity needs to be evaluated so that a personalized …
Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.
I Clark-Lewis, B Dewald, T Geiser… - Proceedings of the …, 1993 - National Acad Sciences
Amino acid deletion and mutagenesis experiments have indicated that the sequences Glu-Leu-Arg
(ELR) preceding the first cysteine at the N terminus of interleukin 8 (IL-8) is required …
(ELR) preceding the first cysteine at the N terminus of interleukin 8 (IL-8) is required …
[HTML][HTML] Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
…, CM Lehr, H Huwer, T Geiser… - Communications …, 2021 - nature.com
The air-blood barrier with its complex architecture and dynamic environment is difficult to
mimic in vitro. Lung-on-a-chips enable mimicking the breathing movements using a thin, …
mimic in vitro. Lung-on-a-chips enable mimicking the breathing movements using a thin, …
Activation of human neutrophils by C3a and C5A Comparison of the effects on shape changes, chemotaxis, secretion, and respiratory burst
MU Ehrengruber, T Geiser, DA Deranleau - FEBS letters, 1994 - Elsevier
The effects of anaphylatoxin C3a on human neutrophils were studied in comparison with C5a.
Both peptides induced a transient shape change response and a respiratory burst. In both …
Both peptides induced a transient shape change response and a respiratory burst. In both …