User profiles for Thomas Braun

Thomas Braun

Max-Planck
Verified email at mpi-BN.MPG.de
Cited by 38664

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

…, MP Scheffer, AS Frangakis, X Yin, M Mayr, T Braun… - Nature cell …, 2012 - nature.com
The shear-responsive transcription factor Krüppel-like factor 2 (KLF2) is a critical regulator
of endothelial gene expression patterns induced by atheroprotective flow. As microRNAs (…

Atomically precise bottom-up fabrication of graphene nanoribbons

J Cai, P Ruffieux, R Jaafar, M Bieri, T Braun… - Nature, 2010 - nature.com
Graphene nanoribbons—narrow and straight-edged stripes of graphene, or single-layer
graphite—are predicted to exhibit electronic properties that make them attractive for the …

Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice

…, S Kostin, T Boettger, T Kubin, T Braun… - Circulation …, 2008 - Am Heart Assoc
Sirt7 is a member of the mammalian sirtuin family consisting of 7 genes, Sirt1 to Sirt7, which
all share a homology to the founding family member, the yeast Sir2 gene. Most sirtuins are …

Functionalization of fluorinated molecules by transition-metal-mediated C–F bond activation to access fluorinated building blocks

T Ahrens, J Kohlmann, M Ahrens, T Braun - Chemical Reviews, 2015 - ACS Publications
Fluorinated organic compounds increasingly gain importance in numerous areas of
chemistry and everyday life. Building blocks which contain fluorinated entities are of high …

Synthesis of fluorinated building blocks by transition‐metal‐mediated hydrodefluorination reactions

MF Kuehnel, D Lentz, T Braun - … Chemie International Edition, 2013 - Wiley Online Library
The activation and functionalization of carbon–fluorine bonds can be considered as a major
challenge in organometallic chemistry. The growing demand for means to introduce fluorine …

[HTML][HTML] Myostatin mutation associated with gross muscle hypertrophy in a child

…, C Hübner, T Riebel, W Kömen, T Braun… - … England Journal of …, 2004 - Mass Medical Soc
Both acquired and inherited disorders of muscle are common; thus, greater understanding
of muscle growth and maintenance is important for future therapies. Myostatin down-regulates …

MyoD or Myf-5 is required for the formation of skeletal muscle

MA Rudnicki, PNJ Schnegelsberg, RH Stead, T Braun… - Cell, 1993 - cell.com
Mice carrying null mutations in the myogenic regulatory factors Myf-5 or YyoD have apparently
normal skeletal muscle. To address whether these two factors functionally substitute for …

[HTML][HTML] Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

…, J Schneider, M Krüger, L Hein, T Braun - The Journal of …, 2009 - Am Soc Clin Investig
VSMCs respond to changes in the local environment by adjusting their phenotype from
contractile to synthetic, a phenomenon known as phenotypic modulation or switching. Failure of …

Prognostic discrimination in" good-risk" chronic granulocytic leukemia

…, S Tura, GA Gomez, JE Robertson, CY Tso, TJ Braun… - 1984 - ashpublications.org
The prognostic significance of disease features recorded at the time of diagnosis was
examined among 813 patients with Philadelphia chromosome- positive, nonblastic chronic …

[PDF][PDF] Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages

…, D Ryan, HT Jacobs, M Szibor, RJ Xavier, T Braun… - Cell, 2016 - cell.com
Activated macrophages undergo metabolic reprogramming, which drives their pro-inflammatory
phenotype, but the mechanistic basis for this remains obscure. Here, we demonstrate …