Background Pneumococcal polysaccharide conjugate vaccines prevent pneumococcal
disease in infants, but their efficacy against pneumococcal community-acquired pneumonia in …

BACKGROUND Since the 1998 European Respiratory Society (ERS) lower respiratory tract
infection (LRTI) guidelines 1 were published, the evidence on which they were based has …

The worldwide increase in resistance to antimicrobial drugs has made reducing the
unnecessary use of antibiotics a public health priority. There have been campaigns in many …

Background High-volume prescribing of antibiotics in primary care is a major driver of
antibiotic resistance. Education of physicians and patients can lower prescribing levels, but it …

Scope The Dutch Working Party on Antibiotic Policy constituted a multidisciplinary expert
committee to provide evidence-based recommendation for the use of antibacterial therapy in …

Background Lower-respiratory-tract infection is one of the most common acute illnesses
managed in primary care. Few placebo-controlled studies of antibiotics have been done, and …

Objective: To determine the effect of antibiotic treatment for acute otitis media in children
between 6 months and 2 years of age. Design: Practice based, double blind, randomised, …

Objectives To quantify the diagnostic accuracy of selected inflammatory markers in addition
to symptoms and signs for predicting pneumonia and to derive a diagnostic tool. Design …

Background and objective: Indicators to measure the quality of healthcare are increasingly
used by healthcare professionals and policy makers. In the context of increasing antimicrobial …

Background Postherpetic neuralgia is the most frequent complication of herpes zoster. Treatment
of this neuropathic pain syndrome is difficult and often disappointing. We assessed the …