Background Anaphylaxis, which is rare, has been reported after COVID‐19 vaccination, but
its management is not standardized. Method Members of the European Network for Drug …

Background Systemic mastocytosis (SM) is a rare disorder of abnormal mast cells in at least
1 extracutaneous organ/tissue. Anaphylaxis is an acute, severe systemic hypersensitivity …

Mastocytosis is a neoplasm characterized by an accumulation of mast cells in various
organs and increased risk for severe anaphylaxis in patients with concomitant allergies. …

In recent years, our knowledge about mechanisms underlying mast cell activation (MCA) and
accumulation in various pathologic conditions increased substantially. In addition, criteria …

Physiologic levels of basal serum tryptase vary among healthy individuals, depending on the
numbers of mast cells, basal secretion rate, copy numbers of the TPSAB1 gene encoding …

Mast cells (MCs) are stationary cells and are present in all vascularized tissues. 1–4
Although their physiologic role is thought to be supporting innate immunity, wound healing, …

Simple Summary The term mastocytosis denotes a heterogeneous group of rare disorders
characterized by abnormal accumulation and activation of mast cells in various organs. …

… panel Jesper Jarkvist MD a b c , Knut Brockow MD, PhD d , Theo Gülen MD, PhD a b c …
Gülen conceptualized and designed the study; collected, analyzed and interpreted the data; and …

Background Anaphylaxis is a well-known feature of mastocytosis, particularly in relation to
hymenoptera venom stings. It is therefore hypothesized that mastocytosis patients may also …

Background Patients with clonal mast cell disorders (cMCD), systemic mastocytosis (SM)
and monoclonal mast cell activation syndrome (MMAS), represent an increased risk for …