Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

T Nakagawa, S Shimizu, T Watanabe, O Yamaguchi… - Nature, 2005 - nature.com
Mitochondria play an important role in energy production, Ca 2+ homeostasis and cell death.
In recent years, the role of the mitochondria in apoptotic and necrotic cell death has …

p38α mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload

…, S Hikoso, Y Higuchi, T Watanabe… - … and cellular biology, 2004 - Taylor & Francis
The molecular mechanism for the transition from cardiac hypertrophy, an adaptive response
to biomechanical stress, to heart failure is poorly understood. The mitogen-activated protein …

Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

…, S Hikoso, T Takeda, T Watanabe… - Proceedings of the …, 2003 - National Acad Sciences
Left ventricular remodeling that occurs after myocardial infarction (MI) and pressure overload
is generally accepted as a determinant of the clinical course of heart failure. The molecular …

Serial angioscopic evidence of incomplete neointimal coverage after sirolimus-eluting stent implantation: comparison with bare-metal stents

…, J Kotani, M Uematsu, T Morozumi, T Watanabe… - Circulation, 2007 - Am Heart Assoc
Background— The time course of neointimal formation after stent implantation has not been
studied extensively by angioscopy in the drug-eluting stent era. Methods and Results— …

[HTML][HTML] Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

O Yamaguchi, T Watanabe, K Nishida… - The Journal of …, 2004 - Am Soc Clin Investig
The Raf/MEK/extracellular signal–regulated kinase (ERK) signaling pathway regulates diverse
cellular processes such as proliferation, differentiation, and apoptosis and is implicated …

Ultra-high dose methylcobalamin promotes nerve regeneration in experimental acrylamide neuropathy

T Watanabe, R Kaji, N Oka, W Bara, J Kimura - Journal of the neurological …, 1994 - Elsevier
Despite intensive searches for therapeutic agents, few substances have been convincingly
shown to enhance nerve regeneration in patients with peripheral neuropathies. Recent …

Robust, high-performance n-type organic semiconductors

…, Y Tani, H Sugiura, T Watanabe, S Watanabe… - Science …, 2020 - science.org
Organic semiconductors (OSCs) are important active materials for the fabrication of next-generation
organic-based electronics. However, the development of n-type OSCs lags behind …

EUV emission lines and diagnostics observed with Hinode/EIS

…, L Culhane, LK Harra, T Watanabe… - Publications of the …, 2007 - academic.oup.com
Quiet Sun and active region spectra from the Hinode/EIS instrument are presented, and the
strongest lines from different temperature regions discussed. A list of emission lines …

Silicon pressure sensor integrates resonant strain gauge on diaphragm

…, H Kuwayama, T Kobayashi, T Watanabe… - Sensors and Actuators A …, 1990 - Elsevier
A novel silicon pressure sensor has been developed which will enable high-precision pressure
measurement. The sensor, which is based on a new concept, is fabricated from a single …

Efficacy of antiarrhythmic drugs short-term use after catheter ablation for atrial fibrillation (EAST-AF) trial

…, I Morishima, F Miura, T Watanabe… - European heart …, 2016 - academic.oup.com
Aims Substantial portion of early arrhythmia recurrence after catheter ablation for atrial fibrillation
(AF) is considered to be due to irritability in left atrium (LA) from the ablation procedure. …