Complete sequencing and characterization of 21,243 full-length human cDNAs

…, S Aotsuka, Y Yoshikawa, H Matsunawa, T Ichihara… - Nature …, 2004 - nature.com
As a base for human transcriptome and functional genomics, we created the “full-length long
Japan” (FLJ) collection of sequenced human cDNAs. We determined the entire sequence …

cDNA microarray assessment for ozone-stressed Arabidopsis thaliana

…, M Aono, A Kubo, S Moriya, T Ichihara… - Environmental …, 2002 - Elsevier
Various detrimental factors in the environment damage plants, resulting in growth inhibition
or withering. However, it is not easy to identify causal factors by visually inspecting the …

[HTML][HTML] Highly sensitive detection of a HER2 12-base pair duplicated insertion mutation in lung cancer using the Eprobe-PCR method

Y Takase, K Usui, K Shimizu, Y Kimura, T Ichihara… - Plos one, 2017 - journals.plos.org
Somatic mutation in human epidermal growth factor receptor-related 2 gene (HER2) is one
of the driver mutations in lung cancer. HER2 mutations are found in about 2% of lung …

[HTML][HTML] Eprobe-mediated screening system for somatic mutations in the KRAS locus

…, M Tagami, Y Takase, T Ichihara… - Oncology …, 2015 - spandidos-publications.com
Activating mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) loci are largely
predictive of resistance to epidermal growth factor receptor (EGFR) therapy in colorectal …

Significance of RAS mutations in pulmonary metastases of patients with colorectal cancer

…, Y Motegi, H Ogawa, N Harimoto, T Ichihara… - International Journal of …, 2020 - Springer
Background RAS/BRAF mutations of colorectal cancer (CRC) play a crucial role in carcinogenesis
and cancer progression and need to be considered for the therapeutic strategy choice…

Detection of drug-resistant Mycobacterium tuberculosis isolates using DNA microarray

Y Yoshikawa, T Ichihara, Y Suzuki - Rinsho Biseibutsu Jinsoku …, 2003 - europepmc.org
Rapid identification of drug-resistant strains of Mycobacterium tuberculosis is an important
problem to adequate patient treatment. However, current clinical assays for determining …

LATE-BREAKING ABSTRACT: Novel rapid screening assay for HER2 duplicated insertion mutation by Eprobe-PCR method

…, K Obayashi, Y Ohtaki, T Nagashima, T Ichihara… - 2015 - Eur Respiratory Soc
Background: Human epidermal growth factor receptor 2(HER2) is one of the driver mutations
of lung cancer. This is a rare somatic mutation, 12-bp duplicated insertion is observed the …

Screening of residents following the Tokyo Electric Fukushima Daiichi nuclear power plant accident

…, K Tanigawa, Y Iwasaki, T Ono, M Ichihara… - Health …, 2013 - journals.lww.com
On 11 March 2011, the Great Eastern Japan Earthquake occurred, causing the accident at
the Fukushima Daiichi Nuclear Power Plant of Tokyo Electric Power Co. Residents were …

Serum level of soluble (pro) renin receptor is modulated in chronic kidney disease

…, K Yuasa, E Hoshino, T Iiyama, A Ichihara… - Clinical and …, 2013 - Springer
Background Prorenin, the precursor of renin, binds to the (pro)renin receptor [(P)RR] and
triggers intracellular signaling. The ligand binding sites of (P)RR are disconnected and are …

Artificial nerve tubes and their application for repair of peripheral nerve injury: an update of current concepts

S Ichihara, Y Inada, T Nakamura - Injury, 2008 - Elsevier
Over the last 20 years, an increasing number of research articles have reported on the use
of artificial nerve tubes to repair nerve defects. The development of an artificial nerve tube as …