Introduction: Patient web portal(PWP)s have been developed by health care providers to
increase transparency and enhance self-management. PWPs generally provide access to …

The association between socioeconomic status (SES) and alcohol-related diseases has
been widely explored. Less is known, however, on whether the association of moderate …

Background Iron deficiency is now accepted as an independent entity beyond anemia.
Recently, a new functional definition of iron deficiency was proposed and proved strong efficacy …

Despite the discovery of heterotrimeric αβγ G proteins ∼25 years ago, their selective perturbation
by cell-permeable inhibitors remains a fundamental challenge. Here we report that the …

Aims Data on the association between periodontitis and preclinical cardiac alterations
remain scarce. The aim of the current study is to determine if periodontitis is associated with …

Aims Although absolute (AID) and functional iron deficiency (FID) are known risk factors for
patients with cardiovascular (CV) disease, their relevance for the general population is …

Somatic gain-of-function mutations of GNAQ and GNA11, which encode α subunits of
heterotrimeric Gα q/11 proteins, occur in about 85% of cases of uveal melanoma (UM), the most …

BACKGROUND: SGLT2 (sodium-glucose cotransporter 2) inhibitors (SGLT2i) can protect the
kidneys and heart, but the underlying mechanism remains poorly understood. METHODS: …

Objectives The biomarker N-terminal pro B-type natriuretic peptide (NT-proBNP) has predictive
value for identifying individuals at risk for cardiovascular disease (CVD). However, it is …

Aim To test the association of alcohol consumption with total and cause‐specific mortality
risk. Design Prospective observational multi‐centre population‐based study. Setting Sixteen …