User profiles for Tal Kaplan

Tal Keren-Kaplan

Verified email at nih.gov
Cited by 1060

Combined morphologic and fluorescence in situ hybridization analysis of voided urine samples for the detection and follow‐up of bladder cancer in patients with …

M Daniely, R Rona, T Kaplan… - … Journal of the …, 2007 - Wiley Online Library
BACKGROUND. Bladder cancer is among the 5 most common malignancies worldwide.
Patients with bladder cancer are closely followed with periodic cystoscopies and urine cytology …

VTX‐1 liquid biopsy system for fully‐automated and label‐free isolation of circulating tumor cells with automated enumeration by BioView platform

E Sollier‐Christen, C Renier, T Kaplan, E Kfir… - Cytometry Part …, 2018 - Wiley Online Library
Clinicians continue to rely on invasive tissue biopsies as a mean to assess a patient's disease
and prescribe appropriate treatment regimens. Biopsies not only are risky and expensive …

Combined analysis of morphology and fluorescence in situ hybridization significantly increases accuracy of bladder cancer detection in voided urine samples

M Daniely, R Rona, T Kaplan, S Olsfanger, L Elboim… - Urology, 2005 - Elsevier
OBJECTIVES: To evaluate a combined analysis approach that involves cytologic evaluation
and fluorescence in situ hybridization analysis for detecting cancer cells in voided urine …

Automatic scanning of interphase FISH for prenatal diagnosis in uncultured amniocytes

…, A Zudik, E Preisler, N Hoffmann, T Kaplan… - Genetic …, 2005 - liebertpub.com
Fluorescence in situ hybridization (FISH) of uncultured amniocytes using chromosome-specific
DNA probes offers the opportunity for rapid aneuploidy screening. Between 80 and 95% …

Computerized analysis of cytology and fluorescence in situ hybridization (FISH) in induced sputum for lung cancer detection

…, R Rona, E Fireman, L Madi, T Kaplan… - Cancer …, 2010 - Wiley Online Library
BACKGROUND: Lung cancer results from a multistep process, whereby genetic and
epigenetic alterations lead to a malignant phenotype. Somatic mutations, deletions, and …

Non-invasive early detection of malignant pulmonary nodules by FISH-based sputum test

…, YA Schwarz, GWS Hoo, RK Batra, G Fink, T Kaplan… - Cancer genetics, 2018 - Elsevier
Background Early detection decreases lung cancer mortality. The Target-FISH Lung Cancer
Detection (LCD) Test is a non-invasive test designed to detect chromosomal changes (…

[HTML][HTML] Identification of Cancer Cells in the Human Body by Anti-Telomerase Peptide Antibody: Towards the Isolation of Circulating Tumor Cells

…, O Wolach, P Raanani, D Peer, T Kaplan… - International Journal of …, 2022 - mdpi.com
Early detection of tumor cells by identifying universal Tumor Associated Antigens (TAA) can
drastically change our diagnostic, theranostic and therapeutic possibilities to cure cancer. …

Circulating tumor cell enumeration and protein expression by CapioCyte and Allegro Plus imaging

J Lim, C Johnson, T Kaplan, MJ Poellmann, Y Harari… - Cancer Research, 2024 - AACR
Radiation or chemoradiation followed by surgical resection is the current standard of therapy
for many diseases. These treatments are increasingly supplemented with monoclonal …

Mechanisms and functions of lysosome positioning

J Pu, CM Guardia, T Keren-Kaplan… - Journal of cell …, 2016 - journals.biologists.com
Lysosomes have been classically considered terminal degradative organelles, but in recent
years they have been found to participate in many other cellular processes, including killing …

[HTML][HTML] RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

T Keren-Kaplan, A Sarić, S Ghosh… - Nature …, 2022 - nature.com
The small GTPase ARL8 associates with endolysosomes, leading to the recruitment of
several effectors that couple endolysosomes to kinesins for anterograde transport along …