User profiles for Takeshi Nabe

Takeshi Nabe

Setsunan University
Verified email at pharm.setsunan.ac.jp
Cited by 3086

Steroid-resistant asthma and neutrophils

T Nabe - Biological and Pharmaceutical Bulletin, 2020 - jstage.jst.go.jp
Asthma patients are classified by phenotype and endotype. Although symptoms in most
asthma patients are well controlled by glucocorticoid treatment, certain populations of severe …

IL-17A promotes the exacerbation of IL-33–induced airway hyperresponsiveness by enhancing neutrophilic inflammation via CXCR2 signaling in mice

N Mizutani, T Nabe, S Yoshino - The Journal of Immunology, 2014 - journals.aai.org
Neutrophilic airway inflammation is a hallmark of patients with severe asthma. Although we
have reported that both IL-33 and IL-17A contributed to IgE-mediated neutrophilic …

The effects of air pollution on structures, proteins and allergenicity of pollen grains

…, A Chehregani, M Moin, M Gholami, S Kohno, T Nabe… - Aerobiologia, 2004 - Springer
The prevalence of allergic disease has increased world wide during the last decades. Pollen
allergy is the most typical form of allergic disease. The increase in its frequency during …

Interleukin‐33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE‐mediated airway inflammation and remodelling in mice

N Mizutani, T Nabe, S Yoshino - Immunology, 2013 - Wiley Online Library
Allergen‐specific IgE has long been regarded as a major molecular component of allergic
asthma. Additionally, there is increasing evidence of the important roles of interleukin‐33 ( IL ‐…

Interleukin (IL)-33: new therapeutic target for atopic diseases

T Nabe - Journal of pharmacological sciences, 2014 - Elsevier
Interleukin (IL)-33, a member of the IL-1 family of cytokines, is produced when epithelial and
endothelial cells are exposed to stimuli. Hematopoietic cells such as macrophages also …

Deficiency of n‐6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis‐like pruritic skin inflammation in special diet‐fed hairless mice

…, N Kawaguchi, S Ohya, S Kohno, T Nabe - Experimental …, 2013 - Wiley Online Library
Hairless mice fed a special diet, HR ‐ AD , develop atopic dermatitis ( AD )‐like skin
inflammation with skin barrier defects and itch‐related scratching; however, the ingredient(s) …

Production of interleukin (IL)-33 in the lungs during multiple antigen challenge-induced airway inflammation in mice, and its modulation by a glucocorticoid

T Nabe, H Wakamori, C Yano, A Nishiguchi… - European journal of …, 2015 - Elsevier
Although interleukin (IL)-33 is a candidate aggravator of asthma, the cellular sources of IL-33
in the lungs during the progression of antigen-induced airway inflammation remain unclear…

[HTML][HTML] Roles of type 1 regulatory T (Tr1) cells in allergen-specific immunotherapy

…, T Terada, K Kitatani, R Kawata, T Nabe - Frontiers in …, 2022 - frontiersin.org
Allergen-specific immunotherapy (AIT) is the only causative treatment for allergic diseases
by modification of the immune response to allergens. A key feature of AIT is to induce …

Sustained effects of intralymphatic pollen-specific immunotherapy on Japanese cedar pollinosis.

…, M Suzuki, Y Inaka, T Inui, M Matsuda, T Nabe… - Rhinology, 2020 - europepmc.org
BACKGROUND: Intralymphatic immunotherapy (ILIT) for allergic patients requires only a
few intralymphatic injections of the allergen. However, the effectiveness and safety for …

Atopic dermatitis‐like pruritic skin inflammation caused by feeding a special diet to HR‐1 hairless mice

M Fujii, J Tomozawa, N Mizutani, T Nabe… - Experimental …, 2005 - Wiley Online Library
Dry skin/barrier dysfunction is considered to be one of the characteristic features of atopic
dermatitis (AD). When HR‐1 hairless mice are fed a special diet, HR‐AD, dry red skin is …