Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non‐neoplastic diseases
T Shiomi, V Lemaître, J D'Armiento… - Pathology …, 2010 - Wiley Online Library
… Takayuki Shiomi and Vincent Lemaître contributed equally to … Takayuki Shiomi and Vincent
Lemaître contributed equally to … Takayuki Shiomi and Vincent Lemaître contributed equally to …
Lemaître contributed equally to … Takayuki Shiomi and Vincent Lemaître contributed equally to …
Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF‐induced angiogenesis
I Inoki, T Shiomi, G Hashimoto, H Enomoto… - The FASEB …, 2002 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a strong angiogenic mitogen and plays
important roles in angiogenesis under various pathophysiological conditions. The in vivo …
important roles in angiogenesis under various pathophysiological conditions. The in vivo …
[PDF][PDF] Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
Age-related loss of muscle mass and force (sarcopenia) contributes to disability and increased
mortality. Ryanodine receptor 1 (RyR1) is the skeletal muscle sarcoplasmic reticulum …
mortality. Ryanodine receptor 1 (RyR1) is the skeletal muscle sarcoplasmic reticulum …
MT1-MMP and MMP-7 in invasion and metastasis of human cancers
T Shiomi, Y Okada - Cancer and metastasis reviews, 2003 - Springer
Previous experimental and biochemical studies on matrix metalloproteinases (MMPs) have
indicated that MMPs are implicated in cancer invasion and metastases. Studies on the …
indicated that MMPs are implicated in cancer invasion and metastases. Studies on the …
[HTML][HTML] MMP-1 drives immunopathology in human tuberculosis and transgenic mice
P Elkington, T Shiomi, R Breen… - The Journal of …, 2011 - Am Soc Clin Investig
Most individuals infected with Mycobacterium tuberculosis develop a latent infection, which
does not progress to active tuberculosis (TB). This occurs, in part, because infected …
does not progress to active tuberculosis (TB). This occurs, in part, because infected …
Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage
H Enomoto, I Inoki, K Komiya, T Shiomi, E Ikeda… - The American journal of …, 2003 - Elsevier
To assess the possible involvement of vascular endothelial growth factor (VEGF) in the
pathology of osteoarthritic (OA) cartilage, we examined the expression of VEGF isoforms and …
pathology of osteoarthritic (OA) cartilage, we examined the expression of VEGF isoforms and …
Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis
…, S Yuasa, K Matsumura, K Kimura, T Shiomi… - Nature medicine, 2006 - nature.com
The avascularity of cardiac valves is abrogated in several valvular heart diseases (VHDs).
This study investigated the molecular mechanisms underlying valvular avascularity and its …
This study investigated the molecular mechanisms underlying valvular avascularity and its …
ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal …
…, A Okada, T Ohtsuka, M Shimoda, T Shiomi… - The American journal of …, 2004 - Elsevier
ADAMs (a disintegrin and metalloproteinases) are multifunctional molecules involved in cell-cell
fusion, cell adhesion, membrane protein shedding, and proteolysis. In the present study…
fusion, cell adhesion, membrane protein shedding, and proteolysis. In the present study…
Expression of ADAMTS4 (aggrecanase‐1) in human osteoarthritic cartilage
S Naito, T Shiomi, A Okada, T Kimura… - Pathology …, 2007 - Wiley Online Library
A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)1, 4, 5, 8, 9 and
15, members of the ADAMTS gene family, have the ability to degrade a major cartilage …
15, members of the ADAMTS gene family, have the ability to degrade a major cartilage …
The extracellular matrix regulates granuloma necrosis in tuberculosis
B Al Shammari, T Shiomi, L Tezera… - The Journal of …, 2015 - academic.oup.com
A central tenet of tuberculosis pathogenesis is that caseous necrosis leads to extracellular
matrix destruction and bacterial transmission. We reconsider the underlying mechanism of …
matrix destruction and bacterial transmission. We reconsider the underlying mechanism of …