Rationale: Periostin is a matricellular protein that is involved in the pathophysiology of allergic
rhinitis, chronic rhinosinusitis, and asthma. Associations of serum periostin with systemic …

Background Asthmatic cough is often refractory to standard treatments such as inhaled
corticosteroids (ICS) and long-acting β 2 agonists (LABA). Tiotropium may modulate cough reflex …

Background: While gastroesophageal reflux disease (GERD) is one of the commonest causes
of subacute/chronic cough along with cough-variant asthma (CVA) and rhinosinusitis, its …

Objective: Gastroesophageal reflux disease (GERD) is an important cause of chronic cough.
Substance P (SP) has been implicated in the pathophysiology of cough. Proton pump …

Background Non-adherence to inhalation regimens is common in asthmatic patients. The
Adherence Starts with Knowledge-12 (ASK-12) survey was developed to detect and address …

Background: Cough-variant asthma (CVA) and cough-predominant asthma (CPA) are the
major causes of persistent cough in Japan. The utility of fractional exhaled nitric oxide (FeNO) …

Background/Aim: The aim of the present study was to determine the clinical value of tumor
marker levels for previously treated NSCLC patients. Patients and Methods: We …

Background Chronic rhinosinusitis (CRS) and asthma are collectively called unified airway
diseases. Periostin has been implicated in the pathophysiologic link of these conditions but …

Background: Despite the close linkage between rhinitis, chronic rhinosinusitis (CRS) and
asthma, relevant biomarkers of both upper and lower airway inflammation are rare. Methods: …

Background: Tyrosine kinase inhibitors (TKIs) directed against epidermal growth factor receptor
(EGFR) are important in the treatment of non-small cell lung cancer (NSCLC), especially …