The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review
AG Fraser, TR Orchard, DP Jewell - Gut, 2002 - gut.bmj.com
Background: There are limited data on factors predicting response to azathioprine and
uncertainty regarding the optimal duration of treatment. Patients and methods: The notes of …
uncertainty regarding the optimal duration of treatment. Patients and methods: The notes of …
A comparison of segmental vs subtotal/total colectomy for colonic Crohn's disease: a meta‐analysis
…, T Athanasiou, AG Heriot, TR Orchard… - Colorectal …, 2006 - Wiley Online Library
Objective Using meta‐analytical techniques the present study evaluated differences in short‐term
and long‐term outcomes of adult patients with colonic Crohn's disease who underwent …
and long‐term outcomes of adult patients with colonic Crohn's disease who underwent …
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …
Extraintestinal manifestations of inflammatory bowel disease
H Williams, D Walker, TR Orchard - Current gastroenterology reports, 2008 - Springer
The idiopathic inflammatory bowel diseases (IBD), Crohn’s disease and ulcerative colitis,
may be complicated by extraintestinal manifestations (EIMs) in up to 40% of patients. Reports …
may be complicated by extraintestinal manifestations (EIMs) in up to 40% of patients. Reports …
Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history
TR Orchard, BP Wordsworth, DP Jewell - Gut, 1998 - gut.bmj.com
Background—Peripheral arthropathy is a well-recognised complication of inflammatory
bowel disease (IBD). Little is known of its natural history, but a variety of joint involvement has …
bowel disease (IBD). Little is known of its natural history, but a variety of joint involvement has …
The molecular classification of the clinical manifestations of Crohn's disease
…, K Mulcahy–Hawes, SE Marshall, TR Orchard… - Gastroenterology, 2002 - Elsevier
BACKGROUND & AIMS:: Crohn's disease is a common inflammatory disorder of the gut
characterized by variation in both location and behavior. Chromosome 16 and the HLA region …
characterized by variation in both location and behavior. Chromosome 16 and the HLA region …
Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes
TR Orchard, CN Chua, T Ahmad, H Cheng, KI Welsh… - Gastroenterology, 2002 - Elsevier
Background & Aims: There are few systematic studies on the natural history or immunogenetic
associations of erythema nodosum (EN) or ocular inflammation in inflammatory bowel …
associations of erythema nodosum (EN) or ocular inflammation in inflammatory bowel …
Diagnostic precision of anti-Saccharomyces cerevisiae antibodies and perinuclear antineutrophil cytoplasmic antibodies in inflammatory bowel disease
…, C Simillis, AW Darzi, TR Orchard… - Official journal of the …, 2006 - journals.lww.com
AIMS The aim of this study was to assess the diagnostic precision of anti Saccharomyces
cerevisiae (ASCA) and perinuclear antineutrophil cytoplasmic antibodies (pANCA) in …
cerevisiae (ASCA) and perinuclear antineutrophil cytoplasmic antibodies (pANCA) in …
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease
TR Orchard, S Thiyagaraja, KI Welsh, BP Wordsworth… - Gastroenterology, 2000 - Elsevier
Background & Aims: The detection of phenotype-determining genes as opposed to disease
susceptibility genes requires precise phenotypic characterization of patients. Peripheral …
susceptibility genes requires precise phenotypic characterization of patients. Peripheral …
Characterization of inflammatory bowel disease with urinary metabolic profiling
…, SD Taylor-Robinson, TR Orchard - Official journal of the …, 2009 - journals.lww.com
… Orchard. Most patients were under the care of Huw JW Thomas, Julian P. Teare, and …
Orchard who all participated in active recruitment. Sample collection: Horace RT Williams, Simon …
Orchard who all participated in active recruitment. Sample collection: Horace RT Williams, Simon …