[HTML][HTML] Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis

…, JAR Portal, J Schneider, T Muley… - Journal of clinical …, 2012 - ncbi.nlm.nih.gov
Purpose Mesothelin is currently considered the best available serum biomarker of malignant
pleural mesothelioma. To examine the diagnostic accuracy and use of serum mesothelin in …

Comprehensive genomic profiles of small cell lung cancer

…, T Kohno, R Iwakawa, K Tsuta, M Noguchi, T Muley… - Nature, 2015 - nature.com
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest
human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 …

SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

…, T Trefzer, NC Kahn, MA Schneider, T Muley… - The EMBO …, 2020 - embopress.org
The SARS ‐CoV‐2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID ‐19 …

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

…, C Ludwig, P Schnabel, H Hoffmann, T Muley… - Nature …, 2012 - nature.com
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis 1 ,
2 , 3 . We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an …

The novel histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification system of lung …

A Warth, T Muley, M Meister, A Stenzinger… - Journal of clinical …, 2012 - ascopubs.org
Purpose Our aim was to analyze and validate the prognostic impact of the novel
International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/…

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

…, P Woll, I Brüske, HE Wichmann, J Manz, TR Muley… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

[HTML][HTML] Targeting RET in patients with RET-rearranged lung cancers: results from the global, multicenter RET registry

…, SI Rothschild, JY Shih, A Warth, T Muley… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose In addition to prospective trials for non–small-cell lung cancers (NSCLCs) that are
driven by less common genomic alterations, registries provide complementary information on …

[PDF][PDF] The integrated genomic landscape of thymic epithelial tumors

…, GB Mills, RA Moore, S Morris, LE Mose, T Muley… - Cancer cell, 2018 - cell.com
Thymic epithelial tumors (TETs) are one of the rarest adult malignancies. Among TETs,
thymoma is the most predominant, characterized by a unique association with autoimmune …

[PDF][PDF] Reduction of liver metastasis stiffness improves response to bevacizumab in metastatic colorectal cancer

…, AF Valls, P Radhakrishnan, J Liang, G Wang, T Muley… - Cancer cell, 2020 - cell.com
Tumors are influenced by the mechanical properties of their microenvironment. Using
patient samples and atomic force microscopy, we found that tissue stiffness is higher in liver …

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

…, Y Chen, J Gosney, T Liloglou, T Muley… - Human molecular …, 2012 - academic.oup.com
Recent genome-wide association studies (GWASs) have identified common genetic variants
at 5p15.33, 6p21–6p22 and 15q25.1 associated with lung cancer risk. Several other …