Background— The vascular remodeling responsible for pulmonary arterial hypertension (PAH)
involves predominantly the accumulation of α-smooth muscle actin–expressing …

We report on an artificially intelligent nanoarray based on molecularly modified gold nanoparticles
and a random network of single-walled carbon nanotubes for noninvasive diagnosis …

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling
of the precapillary pulmonary arteries, with excessive proliferation of vascular cells. Although …

Rationale: Patients with idiopathic pulmonary arterial hypertension (IPAH) present
circulating autoantibodies against vascular wall components. Pathogenic antibodies may be …

Rationale: C-kit + cells, including bone marrow (BM)–derived progenitors and mast cells,
may participate in vascular remodelling. Because recent studies suggest that c-kit may be a …

Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension
(PH) characterized by progressive obstruction of small pulmonary veins and a dismal …

Huertas et al Immune/Endothelial Dysregulation in PAH 1333 comprise pulmonary transmural
inflammatory cell infiltrates with focal vessel wall necrosis and fibrinoid insudation, a …

Immune mechanisms and autoimmunity seem to play a significant role in idiopathic pulmonary
arterial hypertension (IPAH) pathogenesis and/or progression, but the pathophysiology is …

The intrathymic presence of the muscle acetylcholine receptor (AChR) is controversial, and
the nature of the cell(s) expressing it is unclear. We thus analyzed the molecular expression …

Background: Excessive proliferation and apoptosis resistance in pulmonary vascular cells
underlie vascular remodeling in pulmonary arterial hypertension (PAH). Specific treatments …