Background To date, few data on paediatric COVID-19 have been published, and most reports
originate from China. This study aimed to capture key data on children and adolescents …

Rationale: Interferon-γ (IFN-γ) release assays are widely used to diagnose latent infection
with Mycobacterium tuberculosis in adults, but their performance in children remains …

Background Currently, data on treatment, outcome, and prognostic factors in children with
tuberculous meningitis (TBM) in Europe are limited. To date, most existing data on TBM …

Rationale In 2016, a new interferon-gamma release assay (IGRA) was introduced,
QuantiFERON-TB Gold Plus (QFT-Plus), claimed to have improved sensitivity in active tuberculosis (…

Introduction Tuberculous meningitis (TBM) is often diagnostically challenging. Only limited
data exist on the performance of interferon-γ release assays (IGRA) and molecular assays in …

SETTING: In June 2014, we became aware that shortages of purified protein derivative (PPD),
the test substance used for the tuberculin skin test (TST), had occurred in several …

Background Recent reports indicate an ongoing BCG shortage that may influence
immunisation practice. This study aimed to determine current availability of BCG vaccine across …

Background In high-resource settings the survival of immunocompromised (IC) children has
increased and immunosuppressive therapies are increasingly being used. This study aimed …

SciELO - Brasil - Management and outcomes of severe childhood tuberculosis in the
pediatric intensive care setting: can we identify best practices? Management and outcomes of …

Background: Each year, approximately two million adolescents and young adults in the
world become infected with tuberculosis (TB). The problem is that the classification of the …