User profiles for Sveinbjorn Gizurarson

Sveinbjörn Gizurarson

Professor of Clinical Pharmacokinetics and Biopharmaceutics, University of Iceland
Verified email at hi.is
Cited by 5840

[HTML][HTML] Aspirin versus placebo in pregnancies at high risk for preterm preeclampsia

…, H Meiri, S Gizurarson… - … England Journal of …, 2017 - Mass Medical Soc
Background Preterm preeclampsia is an important cause of maternal and perinatal death
and complications. It is uncertain whether the intake of low-dose aspirin during pregnancy …

Anatomical and histological factors affecting intranasal drug and vaccine delivery

S Gizurarson - Current drug delivery, 2012 - ingentaconnect.com
The aim of this review is to provide an understanding of the anatomical and histological structure
of the nasal cavity, which is important for nasal drug and vaccine delivery as well as the …

Animal models for intranasal drug delivery studies. A review article.

S Gizurarson - Acta pharmaceutica nordica, 1990 - europepmc.org
The purpose of this review is to introduce the investigators to sources of information and to
guiding principles regarding the choice of animal models for experimental and clinical studies …

[HTML][HTML] Placental protein 13 (PP13)–a placental immunoregulatory galectin protecting pregnancy

…, I Kovalszky, M Sammar, S Gizurarson… - Frontiers in …, 2014 - frontiersin.org
Galectins are glycan-binding proteins that regulate innate and adaptive immune responses,
and some confer maternal-fetal immune tolerance in eutherian mammals. A chromosome 19 …

Modulation of immune responses using adjuvants to facilitate therapeutic vaccination

…, J Brimnes, S Chernysh, S Gizurarson… - Immunological …, 2020 - Wiley Online Library
Therapeutic vaccination offers great promise as an intervention for a diversity of infectious
and non‐infectious conditions. Given that most chronic health conditions are thought to have …

[HTML][HTML] Evaluation of intranasal delivery route of drug administration for brain targeting

F Erdő, LA Bors, D Farkas, Á Bajza, S Gizurarson - Brain research bulletin, 2018 - Elsevier
The acute or chronic drug treatments for different neurodegenerative and psychiatric disorders
are challenging from several aspects. The low bioavailability and limited brain exposure …

Comparability of Raman spectroscopic configurations: a large scale cross-laboratory study

…, EJ Giamarellos-Bourboulis, S Gizurarson… - Analytical …, 2020 - ACS Publications
The variable configuration of Raman spectroscopic platforms is one of the major obstacles
in establishing Raman spectroscopy as a valuable physicochemical method within real-world …

Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design combating pre-eclampsia

B Huppertz, H Meiri, S Gizurarson… - Human reproduction …, 2013 - academic.oup.com
Background Pre-eclampsia affects 2–7% of all pregnant women and is a major cause of
maternal and fetal morbidity and mortality. The etiology of pre-eclampsia is still unknown but it is …

[HTML][HTML] Galectin 13 (PP13) facilitates remodeling and structural stabilization of maternal vessels during pregnancy

…, T Drobnjak, M Mandala, S Gizurarson… - International Journal of …, 2019 - mdpi.com
Galectins regulate cell growth, proliferation, differentiation, apoptosis, signal transduction,
mRNA splicing, and interactions with the extracellular matrix. Here we focus on the galectins in …

The effect of cilia and the mucociliary clearance on successful drug delivery

S Gizurarson - Biological and Pharmaceutical Bulletin, 2015 - jstage.jst.go.jp
Nasal mucociliary clearance is one of the most important factors affecting nasal delivery of
drugs and vaccines. This is also the most important physiological defense mechanism inside …