[HTML][HTML] Characterisation of COPD heterogeneity in the ECLIPSE cohort

…, DA Lomas, W MacNee, BE Miller, S Rennard… - Respiratory …, 2010 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a complex condition with
pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity of …

[HTML][HTML] Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort

…, C Crim, DA Lomas, BE Miller, S Rennard… - Respiratory …, 2013 - Elsevier
Comorbidities, are common in COPD, have been associated with poor outcomes and are
thought to relate to systemic inflammation. To investigate comorbidities in relation to systemic …

Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort

…, E Wouters, P Bakke, S Rennard… - European …, 2013 - Eur Respiratory Soc
The 2011 Global Initiative for Chronic Obstructive Lung Disease (GOLD) classifies patients
with chronic obstructive pulmonary disease (COPD) into four groups (A to D). We explored …

Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality

…, HO Coxson, C Crim, DA Lomas, BE Miller, S Rennard… - Thorax, 2014 - thorax.bmj.com
Background Coronary artery calcification is pathognomonic of coronary artery disease (CAD).
Whether CAD in patients with COPD is linked to lung function, functional capacity and/or …

Regional distribution of emphysema: correlation of high-resolution CT with pulmonary function tests in unselected smokers.

…, KJ Nelson, D Daughton, JR Spurzem, SI Rennard - Radiology, 1992 - pubs.rsna.org
High-resolution computed tomography (CT) was correlated with pulmonary function tests in
the evaluation of regional emphysema in 59 smokers. The lung was divided into upper (…

Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema

…, R Casaburi, GJ Criner, SM Lutz, SI Rennard… - Thorax, 2014 - thorax.bmj.com
Background There is notable heterogeneity in the clinical presentation of patients with
COPD. To characterise this heterogeneity, we sought to identify subgroups of smokers by …

The association of depressive symptoms with rates of acute exacerbations in patients with COPD: results from a 3-year longitudinal follow-up of the ECLIPSE cohort

…, H Mülerová, K Lavoie, J Vestbo, SI Rennard… - Journal of the American …, 2017 - Elsevier
… Author links open overlay panel Abebaw Mengistu Yohannes PhD, MSc, FCCP a † , Hana
Mülerová PhD b , Kim Lavoie PhD c , Jorgen Vestbo MD d , Steve I. Rennard MD e f , Emile …

Long-term course of depression trajectories in patients with COPD: a 3-year follow-up analysis of the evaluation of COPD longitudinally to identify predictive surrogate …

…, K Lavoie, R Tal-Singer, J Vestbo, SI Rennard… - Chest, 2016 - Elsevier
Background There is insufficient evidence about the long-term course of depressive
symptom trajectories and their impact among patients with COPD. Methods We analysed 3-year …

Efficient vasoactive intestinal polypeptide hydrolyzing autoantibody light chains selected by phage display

…, QS Gao, A Thompson, S Rennard… - … et Biophysica Acta (BBA …, 1996 - Elsevier
An immunoglobulin light chain (L chain) library derived from the peripheral blood lymphocytes
of a patient with asthma was cloned into a phagemid vector. Phage particles displaying L …

Systemic markers of lung function and forced expiratory volume in 1 second decline across diverse cohorts

…, SS Rich, JI Rotter, SI Rennard… - Annals of the …, 2023 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is a complex disease characterized
by airway obstruction and accelerated lung function decline. Our understanding of …