Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis

J Kuehr, J Brauburger, S Zielen, U Schauer… - Journal of Allergy and …, 2002 - Elsevier
Background: Specific immunotherapy (SIT) and treatment with monoclonal anti-IgE antibody
have complementary modes of action. Objective: The purpose of this study was to …

Pappataci-Fieber

M Becker, S Zielen, TF Schwarz, R Linde… - Klinische …, 1997 - thieme-connect.com
Sandfly fever virus is known to cause pappataci fever. The sandfly fever virus belongs to the
Genus Phlebovirus (family: Bunyaviridae) and is endemically found in areas of South Europe…

[HTML][HTML] RSV prevention in all infants: which is the most preferable strategy?

…, F Martinon Torres, M Tsolia, S Zielen - Frontiers in …, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) causes a spectrum of respiratory illnesses in infants and
young children that may lead to hospitalizations and a substantial number of outpatient visits, …

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

…, J Kirschner, T Schmoller, S Zielen… - The lancet respiratory …, 2019 - thelancet.com
Background Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal
antibody that has been shown to safely reduce exacerbations and improve lung function for …

Steroid-sparing effects with allergen-specific immunotherapy in children with asthma: a randomized controlled trial

S Zielen, P Kardos, E Madonini - Journal of allergy and clinical immunology, 2010 - Elsevier
BACKGROUND: Asthma control is now recognized as the main goal of asthma therapy.
Guidelines recommend finding the lowest effective dose of inhaled corticosteroids in children …

Elevated oxidative stress in patients with ataxia telangiectasia

…, D Schindler, K Müller, H Böhles, S Zielen - … and redox signaling, 2002 - liebertpub.com
Ataxia telangiectasia (AT) is a pleiotropic genetic disorder characterized by progressive
neurodegeneration, especially of cerebellar Purkinje cells, immunodeficiency, increased …

Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study

…, S Wanin, J Just, R Linde, S Zielen… - The Lancet …, 2023 - thelancet.com
Background Tezepelumab is a human monoclonal antibody that blocks thymic stromal
lymphopoietin. The drug has been tested previously in the phase 3 NAVIGATOR (NCT03347279) …

Sputum biomarker profiles in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) and association between pulmonary function

…, PC Baer, R Buhl, S Schmitt-Grohé, S Zielen… - Cytokine, 2010 - Elsevier
Lung diseases like cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD)
are associated with chronic airway inflammation. The aim of our study was to compare a …

Real‐world benefits of allergen immunotherapy for birch pollen‐associated allergic rhinitis and asthma

U Wahn, C Bachert, J Heinrich, H Richter, S Zielen - Allergy, 2019 - Wiley Online Library
Background Real‐world evidence is sparse on the benefits of allergen immunotherapy [ AIT
; subcutaneous/sublingual immunotherapy ( SCIT / SLIT )], the only disease‐modifying …

Comprehensive phenotypic characterization of human adipose-derived stromal/stem cells and their subsets by a high throughput technology

PC Baer, S Kuçi, M Krause, Z Kuçi, S Zielen… - Stem cells and …, 2013 - liebertpub.com
The characterization of adipose-derived stromal/stem cells (ASCs) remains difficult due to
the lack of a definitive and unique cellular marker. Therefore, a combination of markers is …