Repurposing of a drug scaffold: Identification of novel sila analogues of rimonabant as potent antitubercular agents

…, A Anand, B Swetha, S Veeraraghavan… - European Journal of …, 2016 - Elsevier
The structural similarity between an MmpL3 inhibitor BM212, and a cannabinoid receptor
modulator rimonabant, prompted us to investigate the anti-tubercular activity of rimonabant and …

Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI-45227 in rat plasma by LC–MS/MS: Application to a pharmacokinetic study

S Veeraraghavan, S Viswanadha, S Thappali… - … of pharmaceutical and …, 2015 - Elsevier
Efficacy assessments using a combination of ibrutinib and lenalidomide necessitate the
development of an analytical method for determination of both drugs in plasma with precision. A …

Design, synthesis, and identification of silicon incorporated oxazolidinone antibiotics with improved brain exposure

…, D Upadhyay, S Veeraraghavan… - ACS Medicinal …, 2015 - ACS Publications
Therapeutic options for brain infections caused by pathogens with a reduced sensitivity to
drugs are limited. Recent reports on the potential use of linezolid in treating brain infections …

Simultaneous quantification of ruxolitinib and nilotinib in rat plasma by LC–MS/MS: Application to a pharmacokinetic study

S Veeraraghavan, S Thappali, S Viswanadha… - … of Pharmaceutical and …, 2014 - Elsevier
Efficacy assessments using a combination of ruxolitinib and nilotinib necessitate the development
of a high precision analytical method for determination of both drugs in plasma. A high …

A first‐in‐human study to evaluate the safety, tolerability and pharmacokinetics of RP3128, an oral calcium release‐activated calcium (CRAC) channel modulator in …

…, S Viswanadha, S Veeraraghavan… - Journal of Clinical …, 2021 - Wiley Online Library
What is known and objective RP3128, a novel, orally available modulator of calcium
released activated calcium (CRAC) channel, is being developed for the potential treatment of …

Simultaneous quantification of baricitinib and methotrexate in rat plasma by LC-MS/MS: Application to a pharmacokinetic study

S Veeraraghavan, SRS Thappali, S Viswanadha… - Scientia …, 2016 - mdpi.com
Efficacy assessments using a combination of baricitinib and methotrexate necessitate the
development of an analytical method for the determination of both drugs in plasma with …

Simultaneous determination of celecoxib, erlotinib, and its metabolite desmethyl-erlotinib (OSI-420) in rat plasma by liquid chromatography/tandem mass spectrometry …

SRS Thappali, K Varanasi, S Veeraraghavan… - Scientia …, 2012 - mdpi.com
A new method for the simultaneous determination of celecoxib, erlotinib, and its active
metabolite desmethyl-erlotinib (OSI-420) in rat plasma, by liquid chromatography/tandem mass …

Simultaneous quantification of idelalisib, fludarabine and lenalidomide in rat plasma by using high-performance liquid chromatography coupled with heated …

S Veeraraghavan, S Thappali, S Viswanadha… - … of Chromatography B, 2014 - Elsevier
A sensitive and reliable high-performance liquid chromatography-mass spectrometry (LC-MS/MS)
method was developed and validated for simultaneous quantification of idelalisib, …

Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N‐oxide in plasma by LC‐MS/MS: application for a pharmacokinetic study

…, KVS Varanasi, S Veeraraghavan… - Journal of mass …, 2012 - Wiley Online Library
A sensitive and reliable high‐performance liquid chromatography–mass spectrometry (LC–MS/MS)
was developed and validated for simultaneous quantification IC87114, roflumilast (…

[HTML][HTML] Rapid LC-ESI-MS-MS method for the simultaneous determination of sitagliptin and pioglitazone in rat plasma and its application to pharmacokinetic study

…, V Laxmikanth, S Shantikumar, V Sridhar… - 2012 - scirp.org
A liquid chromatography tandem mass spectrometry (LC-MS/MS) based method was developed
for the simultaneous monitoring plasma levels of Sitagliptin (STG) and Pioglitazone (PIO…