Practicability of nitrogen multiple‐breath washout measurements in a pediatric cystic fibrosis outpatient setting

…, E Kieninger, C Abbas, S Yammine… - Pediatric …, 2013 - Wiley Online Library
Background Although lung clearance index (LCI) is a sensitive indicator of mild cystic
fibrosis (CF) lung disease, it is rarely measured due to lengthy protocols and the commercial …

Normative data for multiple breath washout outcomes in school-aged Caucasian children

…, M Stahl, A Harper, S Yammine… - European …, 2020 - Eur Respiratory Soc
Background The multiple breath nitrogen washout (N 2 MBW) technique is increasingly
used to assess the degree of ventilation inhomogeneity in school-aged children with lung …

Lung clearance index in cystic fibrosis subjects treated for pulmonary exacerbations

…, P Subbarao, L Welsh, S Yammine… - European …, 2015 - Eur Respiratory Soc
Pulmonary exacerbations are important clinical events for cystic fibrosis (CF) patients. Studies
assessing the ability of the lung clearance index (LCI) to detect treatment response for …

Longitudinal course of clinical lung clearance index in children with cystic fibrosis

BS Frauchiger, S Binggeli, S Yammine… - European respiratory …, 2021 - Eur Respiratory Soc
Background Although the lung clearance index (LCI) is a sensitive marker of small airway
disease in individuals with cystic fibrosis (CF), less is known about longitudinal changes in LCI …

Multiple-breath washout measurements can be significantly shortened in children

S Yammine, F Singer, C Abbas, M Roos, P Latzin - Thorax, 2013 - thorax.bmj.com
Multiple-breath washout (MBW)-derived lung clearance index (LCI) is a sensitive measure of
ventilation inhomogeneity in patients with cystic fibrosis (CF), but LCI measurement is time …

Functional evidence for continued alveolarisation in former preterms at school age?

S Yammine, A Schmidt, O Sutter… - European …, 2016 - Eur Respiratory Soc
Prematurity is the most common disruptor of lung development. The aim of our study was to
examine the function of the more vulnerable peripheral airways in former preterm children by …

[HTML][HTML] Ventilation and perfusion assessed by functional MRI in children with CF: reproducibility in comparison to lung function

…, K Ramsey, F Singer, E Stranzinger, S Yammine… - Journal of Cystic …, 2019 - Elsevier
Background Chronic lung diseases such as cystic fibrosis (CF) can be monitored by imaging
and lung function modalities. Magnetic resonance imaging (MRI) techniques such as matrix …

Normative multiple-breath washout data in school-aged children corrected for sensor error

…, M Stahl, A Harper, S Yammine… - European …, 2022 - Eur Respiratory Soc
The nitrogen (N 2 ) multiple-breath washout (MBW) technique is a lung function test used to
assess ventilation distribution and lung volumes. The lung clearance index (LCI) is a marker …

Elevated lung clearance index in infants with cystic fibrosis shortly after birth

E Kieninger, S Yammine, I Korten… - European …, 2017 - Eur Respiratory Soc
It is not known at what age lung function impairment may arise in children with cystic fibrosis
(CF). We assessed lung function shortly after birth in infants with CF diagnosed by newborn …

Inert gas washout: background and application in various lung diseases

J Usemann, S Yammine, F Singer, P Latzin - Swiss medical weekly, 2017 - zora.uzh.ch
Multiple breath inert gas washout (MBW) is a lung function technique to measure ventilation
inhomogeneity. The technique was developed more than 60 years ago, but not much used …