User profiles for Sophie T. Gohy

sophie gohy

Université catholique de Louvain (IREC-PNEU) - Cliniques universitaires Saint-Luc …
Verified email at uclouvain.be
Cited by 1840

Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition

ST Gohy, C Hupin, C Fregimilicka… - European …, 2015 - Eur Respiratory Soc
In chronic obstructive pulmonary disease (COPD), epithelial changes and subepithelial
fibrosis are salient features in conducting airways. Epithelial-to-mesenchymal transition (EMT) …

Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. Persistence in the cultured epithelium and role of transforming growth …

ST Gohy, BR Detry, M Lecocq, C Bouzin… - American journal of …, 2014 - atsjournals.org
Rationale: The generation of protective secretory IgA relies on the epithelial polymeric
immunoglobulin receptor (pIgR). pIgR expression is reduced in chronic obstructive pulmonary …

Lung lymphoid neogenesis in cystic fibrosis: a model of adaptive responses to bacteria?

ST Gohy, MZ Ladjemi, C Pilette - European Respiratory Journal, 2017 - Eur Respiratory Soc
Cystic fibrosis and non-cystic fibrosis bronchiectasis share as their main clinical hallmark
repeated lung infections by opportunist pathogens. In the normal adult lung, almost no …

SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule

…, Q Garnir, B Gerber, B Ghaye, I Gilard, S Gohy… - Kidney international, 2020 - Elsevier
… Comparisons between groups were performed using an unpaired t test, the Wilcoxon rank-sum
(Mann-Whitney) test, or the χ 2 test, as appropriate. Spearman’s rank test was performed …

[HTML][HTML] The global impact of SARS-CoV-2 in 181 people with cystic fibrosis

…, SC Bell, D Reid, P Wark, E Van Braeckel, S Gohy… - Journal of cystic …, 2020 - Elsevier
With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …

[HTML][HTML] Integrative respiratory follow-up of severe COVID-19 reveals common functional and lung imaging sequelae

…, H Yildiz, B Mwenge, F Aboubakar, S Gohy… - Respiratory …, 2021 - Elsevier
Background COVID-19 pandemic resulted in an unprecedented number of hospitalizations
in general wards and intensive care units (ICU). Severe and critical COVID-19 patients suffer …

Bronchial epithelial IgA secretion is impaired in asthma. Role of IL-4/IL-13

…, C Fregimilicka, C Bouzin, S Gohy… - American journal of …, 2018 - atsjournals.org
Rationale: Asthma is associated with increased lung IgE production, but whether the secretory
IgA system is affected in this disease remains unknown. Objectives: We explored mucosal …

Key role of the epithelium in chronic upper airways diseases

S Gohy, C Hupin, MZ Ladjemi, V Hox… - … & Experimental Allergy, 2020 - Wiley Online Library
Key role of the epithelium in chronic upper airways diseases - Gohy - 2020 - Clinical & … while
the mucosa is typically infiltrated by eosinophils, T helper 2 (Th2) lymphocytes, mast cells …

[HTML][HTML] Airway epithelium dysfunction in cystic fibrosis and COPD

V De Rose, K Molloy, S Gohy, C Pilette… - Mediators of …, 2018 - hindawi.com
Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene, whereas chronic
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …

[HTML][HTML] Secretory immunoglobulin a immunity in chronic obstructive respiratory diseases

C de Fays, FM Carlier, S Gohy, C Pilette - Cells, 2022 - mdpi.com
Gohy, ST Polymeric immunoglobulin receptor down-regulation in chronic obstructive
pulmonary disease. Persistence in the cultured epithelium and role of transforming growth factor-…