User profiles for Sophie T. Gohy
sophie gohyUniversité catholique de Louvain (IREC-PNEU) - Cliniques universitaires Saint-Luc … Verified email at uclouvain.be Cited by 1840 |
Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition
ST Gohy, C Hupin, C Fregimilicka… - European …, 2015 - Eur Respiratory Soc
In chronic obstructive pulmonary disease (COPD), epithelial changes and subepithelial
fibrosis are salient features in conducting airways. Epithelial-to-mesenchymal transition (EMT) …
fibrosis are salient features in conducting airways. Epithelial-to-mesenchymal transition (EMT) …
Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. Persistence in the cultured epithelium and role of transforming growth …
ST Gohy, BR Detry, M Lecocq, C Bouzin… - American journal of …, 2014 - atsjournals.org
Rationale: The generation of protective secretory IgA relies on the epithelial polymeric
immunoglobulin receptor (pIgR). pIgR expression is reduced in chronic obstructive pulmonary …
immunoglobulin receptor (pIgR). pIgR expression is reduced in chronic obstructive pulmonary …
Lung lymphoid neogenesis in cystic fibrosis: a model of adaptive responses to bacteria?
Cystic fibrosis and non-cystic fibrosis bronchiectasis share as their main clinical hallmark
repeated lung infections by opportunist pathogens. In the normal adult lung, almost no …
repeated lung infections by opportunist pathogens. In the normal adult lung, almost no …
SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule
… Comparisons between groups were performed using an unpaired t test, the Wilcoxon rank-sum
(Mann-Whitney) test, or the χ 2 test, as appropriate. Spearman’s rank test was performed …
(Mann-Whitney) test, or the χ 2 test, as appropriate. Spearman’s rank test was performed …
[HTML][HTML] The global impact of SARS-CoV-2 in 181 people with cystic fibrosis
With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …
[HTML][HTML] Integrative respiratory follow-up of severe COVID-19 reveals common functional and lung imaging sequelae
…, H Yildiz, B Mwenge, F Aboubakar, S Gohy… - Respiratory …, 2021 - Elsevier
Background COVID-19 pandemic resulted in an unprecedented number of hospitalizations
in general wards and intensive care units (ICU). Severe and critical COVID-19 patients suffer …
in general wards and intensive care units (ICU). Severe and critical COVID-19 patients suffer …
Bronchial epithelial IgA secretion is impaired in asthma. Role of IL-4/IL-13
…, C Fregimilicka, C Bouzin, S Gohy… - American journal of …, 2018 - atsjournals.org
Rationale: Asthma is associated with increased lung IgE production, but whether the secretory
IgA system is affected in this disease remains unknown. Objectives: We explored mucosal …
IgA system is affected in this disease remains unknown. Objectives: We explored mucosal …
Key role of the epithelium in chronic upper airways diseases
Key role of the epithelium in chronic upper airways diseases - Gohy - 2020 - Clinical & … while
the mucosa is typically infiltrated by eosinophils, T helper 2 (Th2) lymphocytes, mast cells …
the mucosa is typically infiltrated by eosinophils, T helper 2 (Th2) lymphocytes, mast cells …
[HTML][HTML] Airway epithelium dysfunction in cystic fibrosis and COPD
Cystic fibrosis is a genetic disease caused by mutations in the CFTR gene, whereas chronic
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …
obstructive pulmonary disease (COPD) is mainly caused by environmental factors (mostly …
[HTML][HTML] Secretory immunoglobulin a immunity in chronic obstructive respiratory diseases
… Gohy, ST Polymeric immunoglobulin receptor down-regulation in chronic obstructive
pulmonary disease. Persistence in the cultured epithelium and role of transforming growth factor-…
pulmonary disease. Persistence in the cultured epithelium and role of transforming growth factor-…