SiiE Is Secreted by the Salmonella enterica Serovar Typhimurium Pathogenicity Island 4-Encoded Secretion System and Contributes to Intestinal Colonization in …

E Morgan, AJ Bowen, SC Carnell, TS Wallis… - Infection and …, 2007 - Am Soc Microbiol
Here we report that Salmonella enterica serovar Typhimurium pathogenicity island 4 carries
a type I secretion system (siiCDF) which secretes an ∼600-kDa protein (encoded by siiE). …

Role in virulence and protective efficacy in pigs of Salmonella enterica serovar Typhimurium secreted components identified by signature-tagged mutagenesis

SC Carnell, A Bowen, E Morgan, DJ Maskell… - …, 2007 - microbiologyresearch.org
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a zoonotic enteric pathogen
of worldwide importance and pigs are a significant reservoir of human infection. Signature-…

The top 10 research priorities in diabetes and pregnancy according to women, support networks and healthcare professionals

…, I Berneantu, N Breslin, C Byrne, S Carnell… - Diabetic …, 2021 - Wiley Online Library
Aims To undertake a Priority Setting Partnership (PSP) to establish priorities for future
research in diabetes and pregnancy, according to women with experience of pregnancy, and …

Norepinephrine Augments Salmonella enterica-Induced Enteritis in a Manner Associated with Increased Net Replication but Independent of the Putative Adrenergic …

GD Pullinger, SC Carnell, FF Sharaff… - Infection and …, 2010 - Am Soc Microbiol
Stress has long been correlated with susceptibility to microbial infection. One explanation
for this phenomenon is the ability of pathogens to sense and respond to host stress-related …

Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial

…, H Mossop, T Homer, T Chadwick, W King, S Carnell… - bmj, 2022 - bmj.com
Objective To test and compare the efficacy of methenamine hippurate for prevention of recurrent
urinary tract infections with the current standard prophylaxis of daily low dose antibiotics…

Adjuvant rituximab—Exploratory trial in young people with Graves disease

…, CA Steele, N Zammitt, S Carnell… - The Journal of …, 2022 - academic.oup.com
Context Remission rates in young people with Graves hyperthyroidism are less than 25%
after 2 years of thionamide antithyroid drug (ATD). Objective We explored whether rituximab (…

[HTML][HTML] ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR): study protocol for a multicentre, pragmatic …

…, A Ali, A Abouhajar, C Brennand, H Brown, S Carnell… - Trials, 2018 - Springer
Background At least half of all adult women will experience infective cystitis (urinary tract
infection: UTI) at least once in their life and many suffer from repeated episodes. Recurrent …

Surgical treatment for recurrent bulbar urethral stricture: a randomised open-label superiority trial of open urethroplasty versus endoscopic urethrotomy (the OPEN trial …

B Goulao, S Carnell, J Shen, G MacLennan, J Norrie… - European Urology, 2020 - Elsevier
Background Urethral stricture affects 0.9% of men. Initial treatment is urethrotomy.
Approximately, half of the strictures recur within 4 yr. Options for further treatment are repeat …

[HTML][HTML] 6-hydroxydopamine-mediated release of norepinephrine increases faecal excretion of Salmonella enterica serovar Typhimurium in pigs

GD Pullinger, PM Van Diemen, SC Carnell… - Veterinary …, 2010 - ncbi.nlm.nih.gov
Salmonella enterica serovar Typhimurium is an animal and zoonotic pathogen of worldwide
importance. In pigs, transport and social stress are associated with reactivation and spread …

[HTML][HTML] Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT.

R Pickard, B Goulao, S Carnell, J Shen… - Health Technology …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Men who suffer recurrence of bulbar urethral stricture have to decide
between endoscopic urethrotomy and open urethroplasty to manage their urinary symptoms. …