Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia

…, R Maggio, N Peragine, S Santangelo… - Blood, The Journal …, 2007 - ashpublications.org
MicroRNAs (miRNAs) are a novel class of small noncoding RNAs that modulate the expression
of genes at the posttranscriptional level. These small molecules have been shown to be …

BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells

…, F Citarella, MR Ricciardi, S Santangelo… - Blood, The Journal …, 2008 - ashpublications.org
Chronic lymphocytic leukemia (CLL) patients exhibit a variable clinical course. To investigate
the association between clinicobiologic features and responsiveness of CLL cells to anti-…

[HTML][HTML] ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression

…, MS De Propris, N Peragine, S Santangelo… - …, 2012 - ncbi.nlm.nih.gov
… Anna Guarini, 1 Marilisa Marinelli, 1 Simona Tavolaro, 1 Emanuele Bellacchio, 2 Monia
Magliozzi, 2 Sabina Chiaretti, 1 Maria Stefania De Propris, 1 Nadia Peragine, 1 Simona …

Spontaneous regression of chronic lymphocytic leukemia: clinical and biologic features of 9 cases

…, F Mancini, N Peragine, S Santangelo… - Blood, The Journal …, 2009 - ashpublications.org
In chronic lymphocytic leukemia (CLL), spontaneous regressions are an exceptional phenomenon,
whose biologic features are unknown. We describe 9 CLL patients who underwent a …

Pre-polysomnographic assessment using the Pittsburgh Sleep Quality Index questionnaire is not useful in identifying people at higher risk for obstructive sleep apnea

…, G Abbruzzese, S Santangelo… - Journal of medical …, 2013 - journals.sagepub.com
Background Polysomnography remains the diagnostic gold standard for obstructive sleep
apnea syndrome (OSAS), but it is time consuming and requires dedicated personnel and …

Stereotyped subset# 1 chronic lymphocytic leukemia: a direct link between B‐cell receptor structure, function, and patients' prognosis

I Del Giudice, S Chiaretti, S Santangelo… - American journal of …, 2014 - Wiley Online Library
Chronic lymphocytic leukemia (CLL) with stereotyped B‐cell receptor (BCR) belonging to
subset #1 (IGHV1‐5‐7/IGKV1‐39) display a poor outcome. To characterize their genetic and …

Behind the scenes of non‐nodal MCL: downmodulation of genes involved in actin cytoskeleton organization, cell projection, cell adhesion, tumour invasion, TP53 …

…, M Messina, S Chiaretti, S Santangelo… - British journal of …, 2012 - Wiley Online Library
Mantle cell lymphoma (MCL) is an aggressive neoplasm with a short survival. Cases with
leukaemic MCL and splenomegaly without adenopathies (non‐nodal MCL) may have a more …

Alpha-1 antitrypsin deficiency: current perspective from genetics to diagnosis and therapeutic approaches

S Santangelo, S Scarlata, ML Poeta… - Current medicinal …, 2017 - ingentaconnect.com
Alpha-1 antitrypsin (A1AT) is a 52-kDa, acute phase glycoprotein encoded by the protease
inhibitor (PI) locus, located on the long arm of chromosome 14 (14q31-32.3). Its structure is …

Relationship between FEV1 and arterial stiffness in elderly people with chronic obstructive pulmonary disease

…, F Battistoni, D Chiurco, S Santangelo… - Aging clinical and …, 2017 - Springer
Background Chronic obstructive pulmonary disease (COPD) is highly prevalent in the elderly,
and both COPD and age per se are associated with cardiovascular morbidity. Aims We …

[HTML][HTML] The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of …

P Sitarek, T Kowalczyk, S Santangelo, AJ Białas… - Neurochemical …, 2018 - Springer
The aim of this study was to determine the anticancer potential of Leonurus sibiricus extract
derived from in vitro transgenic roots transformed by Agrobacetrium rhizogenes with AtPAP1 …