Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …

Background DNA methylation profiles associated with childhood asthma might provide
novel insights into disease pathogenesis. We did an epigenome-wide association study to …

Background: Prenatal exposure to air pollution is considered to be associated with adverse
effects on child health. This may partly be mediated by mechanisms related to DNA …

Birthweight is associated with health outcomes across the life course, DNA methylation may
be an underlying mechanism. In this meta-analysis of epigenome-wide association studies …

Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …

Rationale: Recent evidence highlights the importance of optimal lung development during
childhood for health throughout life. Objectives: To explore the plasticity of individual lung …

Background Preterm birth and shorter duration of pregnancy are associated with increased
morbidity in neonatal and later life. As the epigenome is known to have an important role …

Background: Long-term exposure to ambient air pollution can lead to adverse health effects
in children; however, underlying biological mechanisms are not fully understood. Objectives: …

Background In somatic cancer genomes, delineating genuine driver mutations against a
background of multiple passenger events is a challenging task. The difficulty of determining …

Background The beneficial effect of improving air quality on lung function development remains
understudied. We assessed associations of changes in ambient air pollution levels with …