[HTML][HTML] Diagnostic and prognostic significances of MUC5B and TTF-1 expressions in resected non-small cell lung cancer

R Nagashio, J Ueda, S Ryuge, H Nakashima… - Scientific reports, 2015 - nature.com
To investigate the relationships between the expression of MUC5B and clinicopathological
parameters, the expression of MUC5B was immunohistochemically studied. MUC5B …

Calnexin is a novel sero-diagnostic marker for lung cancer

…, R Nagashio, SX Jiang, K Saito, B Tsuchiya, S Ryuge… - Lung Cancer, 2015 - Elsevier
To develop sero-diagnostic markers for lung cancer, we generated monoclonal antibodies
using lung adenocarcinoma (AC)-derived A549 cells as antigens by employing the random …

[HTML][HTML] Prognostic significance of MYH9 expression in resected non-small cell lung cancer

…, SX Jiang, M Kobayashi, R Nagashio, S Ryuge… - PLoS one, 2015 - journals.plos.org
Introduction Myosin-9 (MYH9) belongs to the myosin superfamily of actin-binding motor protein.
Recently, MYH9 has been thought to be associated with cancer cell migration, invasion, …

[HTML][HTML] Circulating tumor cells as a prognostic factor in patients with small cell lung cancer

S Igawa, K Gohda, T Fukui, S Ryuge… - Oncology …, 2014 - spandidos-publications.com
The detection of circulating tumor cells (CTCs) in peripheral blood is currently an important
field of study. Detection of CTCs by the OBP‑401 assay (TelomeScan®) has previously been …

Expression of RACK1 is a novel biomarker in pulmonary adenocarcinomas

…, T Matsumoto, T Kageyama, Y Satoh, R Shinichiro… - Lung cancer, 2010 - Elsevier
To develop useful early and/or differential diagnostic markers for pulmonary adenocarcinomas,
we generated monoclonal antibodies using A549 cells derived from pulmonary …

Impact of PD-L1 expression in patients with surgically resected non-small-cell lung cancer

S Igawa, Y Sato, S Ryuge, M Ichinoe, K Katono… - Oncology, 2017 - karger.com
Background: Immunotherapy can become a crucial therapeutic option to improve the prognosis
of patients with non-small-cell lung cancer (NSCLC). Here, we evaluated the impact of …

Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats

…, K Katono, M Iwasaki, S Ryuge… - Oncology …, 2008 - spandidos-publications.com
One of the dose-limiting toxicities of irinotecan (CPT-11) is delayed-onset diarrhea, which is
the greatest barrier to treatment with CPT-11-containing regimens. CPT-11 is converted to its …

[HTML][HTML] CAXII Is a sero-diagnostic marker for lung cancer

M Kobayashi, T Matsumoto, S Ryuge, K Yanagita… - PloS one, 2012 - journals.plos.org
To develop sero-diagnostic markers for lung cancer, we generated monoclonal antibodies
using pulmonary adenocarcinoma (AD)-derived A549 cells as antigens by employing the …

Prognostic significance of nestin expression in resected non-small cell lung cancer

S Ryuge, Y Sato, GQ Wang, T Matsumoto, SX Jiang… - Chest, 2011 - Elsevier
Background Nestin is a class 6 intermediate filament protein expressed in stem/progenitor
cells during CNS development. Nestin expression has been detected in many kinds of tumors …

[PDF][PDF] S100A16 is a prognostic marker for lung adenocarcinomas

…, M Kobayashi, R Nagashio, S Ryuge… - … Pacific Journal of …, 2015 - pdfs.semanticscholar.org
Background: Many functional molecules controlling diverse cellular function are included in
low-molecular weight proteins and peptides. Materials and Methods: To identify proteins …