User profiles for Shin-ichi Inoue

Shin-Ichi Inoue

Nagasaki University, Graduate School of Biomedical Sciences, Division of Immunology
Verified email at nagasaki-u.ac.jp
Cited by 1156

[HTML][HTML] Recent advances in RASopathies

Y Aoki, T Niihori, S Inoue, Y Matsubara - Journal of human genetics, 2016 - nature.com
RASopathies or RAS/mitogen-activated protein kinase (MAPK) syndromes are a group of
phenotypically overlapping syndromes caused by germline mutations that encode components …

[HTML][HTML] Roles of IFN-γ and γδ T cells in protective immunity against blood-stage malaria

SI Inoue, M Niikura, S Mineo, F Kobayashi - Frontiers in immunology, 2013 - frontiersin.org
Malaria is caused by infection with Plasmodium parasites. Various studies with knockout
mice have indicated that IFN-γ plays essential roles in protective immunity against blood-stage …

Atrium as a source of brain natriuretic polypeptide in patients with atrial fibrillation

SI Inoue, YO Murakami, K Sano, H Katoh… - Journal of cardiac …, 2000 - Elsevier
Background: Plasma brain natriuretic polypeptide (BNP) levels have been used as biochemical
markers of systolic left ventricular (LV) dysfunction. Although in vitro studies have shown …

[PDF][PDF] Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome

…, T Nagashima, K Nakayama, S Inoue… - The American Journal of …, 2013 - cell.com
RAS GTPases mediate a wide variety of cellular functions, including cell proliferation, survival,
and differentiation. Recent studies have revealed that germline mutations and mosaicism …

[HTML][HTML] Role of interleukin-10 in malaria: focusing on coinfection with lethal and nonlethal murine malaria parasites

M Niikura, SI Inoue, F Kobayashi - BioMed Research International, 2011 - hindawi.com
Interleukin- (IL-) 10, anti-inflammatory cytokine, is known to inhibit the protective immune
responses against malaria parasites and to be involved in exacerbating parasitemia during …

Mitochondria-related male infertility

…, T Morita, H Tanaka, SI Inoue… - Proceedings of the …, 2006 - National Acad Sciences
Approximately 15% of human couples are affected by infertility, and about half of these cases
of infertility can be attributed to men, through low sperm motility (asthenozoospermia) or/…

Crystallographic classification of kink bands in an extruded Mg–Zn–Y alloy using intragranular misorientation axis analysis

M Yamasaki, K Hagihara, S Inoue, JP Hadorn… - Acta materialia, 2013 - Elsevier
Within extruded Mg 89 Zn 4 Y 7 (at.%) alloys containing a long period stacking ordered (LPSO)
phase a unique deformation mode referred to as “kink deformation” is found to occur …

Diagnosis of cardiac sarcoidosis and evaluation of the effects of steroid therapy by gadolinium-DTPA–enhanced magnetic resonance imaging

…, K Ochiai, H Tsukihashi, M Fukui, S Inoue… - The American journal of …, 2001 - Elsevier
BACKGROUND: Cardiac involvement is an important prognostic factor in patients with
sarcoidosis. In this study, we evaluated the usefulness of gadolinium-DTPA (diethylene triamine …

Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation

…, K Nakada, K Ishikawa, SI Inoue… - Proceedings of the …, 2005 - National Acad Sciences
Pathogenic mutations in mtDNAs have been shown to be responsible for expression of
respiration defects and resultant expression of mitochondrial diseases. This study directly …

Amino alcohol effects on the ruthenium (II)-catalysed asymmetric transfer hydrogenation of ketones in propan-2-ol

J Takehara, S Hashiguchi, A Fujii, S Inoue… - Chemical …, 1996 - pubs.rsc.org
Amino alcohol effects on the ruthenium(I1)-catalysed asymmetric transfer hydrogenation of
ketones in propan-2-01 Page 1 Amino alcohol effects on the ruthenium(I1)-catalysed …