Annexin‐1 signals mitogen‐stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2
T Khau, SY Langenbach, M Schuliga… - The FASEB …, 2011 - Wiley Online Library
The role of the calcium‐ and phospho‐lipid‐binding protein annexin I (ANXA1) in cell cycle
regulation has been investigated in estrogen receptor (ER)‐positive MCF‐7 and ER‐…
regulation has been investigated in estrogen receptor (ER)‐positive MCF‐7 and ER‐…
Cellular microenvironment stiffness regulates eicosanoid production and signaling pathways
…, T Harris, J Jaffar, F Jativa, S Langenbach… - American Journal of …, 2020 - atsjournals.org
Pathological changes in the biomechanical environment are implicated in the progression
of idiopathic pulmonary fibrosis (IPF). Stiffened matrix augments fibroblast proliferation and …
of idiopathic pulmonary fibrosis (IPF). Stiffened matrix augments fibroblast proliferation and …
[HTML][HTML] ACE2 expression in organotypic human airway epithelial cultures and airway biopsies
Q Chen, S Langenbach, M Li, YC Xia, X Gao… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by infection with the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is an acute respiratory disease with systemic …
syndrome coronavirus 2 (SARS-CoV-2) is an acute respiratory disease with systemic …
Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity
…, J Jaffar, A Berhan, S Langenbach… - … of Physiology-Lung …, 2017 - journals.physiology.org
In lung injury and disease, including idiopathic pulmonary fibrosis (IPF), extravascular factor
X is converted into factor Xa (FXa), a coagulant protease with fibrogenic actions. …
X is converted into factor Xa (FXa), a coagulant protease with fibrogenic actions. …
[HTML][HTML] Casein kinase 1δ/ε inhibitor, PF670462 attenuates the fibrogenic effects of transforming growth factor-β in pulmonary fibrosis
Transforming growth factor-beta (TGF-β) is a major mediator of fibrotic diseases, including
idiopathic pulmonary fibrosis (IPF). However, therapeutic global inhibition of TGF-β is limited …
idiopathic pulmonary fibrosis (IPF). However, therapeutic global inhibition of TGF-β is limited …
[HTML][HTML] Glucocorticoid insensitivity in virally infected airway epithelial cells is dependent on transforming growth factor-β activity
Asthma and chronic obstructive pulmonary disease (COPD) exacerbations are commonly
associated with respiratory syncytial virus (RSV), rhinovirus (RV) and influenza A virus (IAV) …
associated with respiratory syncytial virus (RSV), rhinovirus (RV) and influenza A virus (IAV) …
In vitro and in vivo evidence for anti-inflammatory properties of 2-methoxyestradiol
2-Methoxyestradiol (2MEO) is an endogenous metabolite of 17β-estradiol that interacts with
estrogen receptors and microtubules. It has acute anti-inflammatory activity in animal …
estrogen receptors and microtubules. It has acute anti-inflammatory activity in animal …
Functional expression of IgG-Fc receptors in human airway smooth muscle cells
…, M Powell, T Harris, SY Langenbach… - American journal of …, 2011 - atsjournals.org
IgE-Fc receptors and IgG-Fc receptors are expressed on hematopoietic cells, but some
evidence suggests that these receptors are also found on nonhematopoietic cells, including …
evidence suggests that these receptors are also found on nonhematopoietic cells, including …
[HTML][HTML] IL-17A and serum amyloid A are elevated in a cigarette smoke cessation model associated with the persistence of pigmented macrophages, neutrophils and …
MJ Hansen, SPJ Chan, SY Langenbach, LF Dousha… - PLoS …, 2014 - journals.plos.org
While global success in cessation advocacy has seen smoking rates fall in many developed
countries, persistent lung inflammation in ex-smokers is an increasingly important clinical …
countries, persistent lung inflammation in ex-smokers is an increasingly important clinical …
Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2
Plasminogen has a role in airway inflammation. Airway smooth muscle (ASM) cells cleave
plasminogen into plasmin, a protease with proinflammatory activity. In this study, the effect of …
plasminogen into plasmin, a protease with proinflammatory activity. In this study, the effect of …