[HTML][HTML] Cellular immune correlates of protection against symptomatic pandemic influenza
S Sridhar, S Begom, A Bermingham, K Hoschler… - Nature medicine, 2013 - nature.com
The role of T cells in mediating heterosubtypic protection against natural influenza illness in
humans is uncertain. The 2009 H1N1 pandemic (pH1N1) provided a unique natural …
humans is uncertain. The 2009 H1N1 pandemic (pH1N1) provided a unique natural …
[HTML][HTML] Effect of dengue serostatus on dengue vaccine safety and efficacy
Background In efficacy trials of a tetravalent dengue vaccine (CYD-TDV), excess hospitalizations
for dengue were observed among vaccine recipients 2 to 5 years of age. Precise risk …
for dengue were observed among vaccine recipients 2 to 5 years of age. Precise risk …
[HTML][HTML] Influenza vaccination strategies: comparing inactivated and live attenuated influenza vaccines
S Sridhar, KA Brokstad, RJ Cox - Vaccines, 2015 - mdpi.com
Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics.
Influenza vaccination is the major method of prophylaxis. Currently annual influenza …
Influenza vaccination is the major method of prophylaxis. Currently annual influenza …
Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis
A Roy, M Eisenhut, RJ Harris, LC Rodrigues, S Sridhar… - Bmj, 2014 - bmj.com
Objectives To determine whether BCG vaccination protects against Mycobacterium
tuberculosis infection as assessed by interferon γ release assays (IGRA) in children. Design …
tuberculosis infection as assessed by interferon γ release assays (IGRA) in children. Design …
[HTML][HTML] Heterosubtypic T-cell immunity to influenza in humans: challenges for universal T-cell influenza vaccines
S Sridhar - Frontiers in immunology, 2016 - frontiersin.org
Influenza A virus (IAV) remains a significant global health issue causing annual epidemics,
pandemics, and sporadic human infections with highly pathogenic avian or swine influenza …
pandemics, and sporadic human infections with highly pathogenic avian or swine influenza …
[HTML][HTML] Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective …
…, H Burgess, B Mann, A Imran, S Sridhar… - The Lancet Infectious …, 2018 - thelancet.com
Background Tackling tuberculosis requires testing and treatment of latent tuberculosis in
high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin …
high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin …
Safety and immunogenicity of an AS03-adjuvanted SARS-CoV-2 recombinant protein vaccine (CoV2 preS dTM) in healthy adults: interim findings from a phase 2 …
S Sridhar, A Joaquin, MI Bonaparte… - The Lancet Infectious …, 2022 - thelancet.com
Background We evaluated our SARS-CoV-2 prefusion spike recombinant protein vaccine (CoV2
preS dTM) with different adjuvants, unadjuvanted, and in a one-injection and two-…
preS dTM) with different adjuvants, unadjuvanted, and in a one-injection and two-…
Single‐dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei
A Reyes‐Sandoval, S Sridhar… - European journal of …, 2008 - Wiley Online Library
Simian adenoviral vectors (SAd) offer an attractive alternative to standard human adenovirus
serotype 5 (AdH5) subunit vaccination, due to pre‐existing immunity affecting vaccine …
serotype 5 (AdH5) subunit vaccination, due to pre‐existing immunity affecting vaccine …
Clinical development of Ebola vaccines
S Sridhar - Therapeutic advances in vaccines, 2015 - journals.sagepub.com
The ongoing outbreak of Ebola virus disease in West Africa highlighted the lack of a licensed
drug or vaccine to combat the disease and has renewed the urgency to develop a pipeline …
drug or vaccine to combat the disease and has renewed the urgency to develop a pipeline …
[HTML][HTML] Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis
…, M Wickremasinghe, S Bremang, M Magtoto, S Sridhar… - PloS one, 2010 - journals.plos.org
Background IFN-γ and IL-2 cytokine-profiles define three functional T-cell subsets which may
correlate with pathogen load in chronic intracellular infections. We therefore investigated …
correlate with pathogen load in chronic intracellular infections. We therefore investigated …