The endothelium in sepsis: source of and a target for inflammation
CE Hack, S Zeerleder - Critical care medicine, 2001 - journals.lww.com
Conclusions The endothelium is a key organ involved in the pathogenesis of sepsis. Dysfunction
of or injury to the endothelium may be involved in the pathogenesis of multiple organ …
of or injury to the endothelium may be involved in the pathogenesis of multiple organ …
Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting
…, DJ Kuter, M Michel, M Montillo, A Röth, SS Zeerleder… - Blood reviews, 2020 - Elsevier
Autoimmune hemolytic anemias (AIHAs) are rare and heterogeneous disorders characterized
by the destruction of red blood cells through warm or cold antibodies. There is currently no …
by the destruction of red blood cells through warm or cold antibodies. There is currently no …
Disseminated intravascular coagulation in sepsis
S Zeerleder, CE Hack, WA Wuillemin - Chest, 2005 - Elsevier
Disseminated intravascular coagulation is a frequent complication of sepsis. Coagulation
activation, inhibition of fibrinolysis, and consumption of coagulation inhibitors lead to a …
activation, inhibition of fibrinolysis, and consumption of coagulation inhibitors lead to a …
Elevated nucleosome levels in systemic inflammation and sepsis
S Zeerleder, B Zwart, WA Wuillemin… - Critical care …, 2003 - journals.lww.com
… Zeerleder, Sacha MD; Zwart, Bas MD; Wuillemin, Walter A. MD, PhD; Aarden, Lucien A.
PhD; Groeneveld, AB Johan MD; Caliezi, Christoph MD; van Nieuwenhuijze, Annemarie EM; …
PhD; Groeneveld, AB Johan MD; Caliezi, Christoph MD; van Nieuwenhuijze, Annemarie EM; …
Circulating nucleosomes and neutrophil activation as risk factors for deep vein thrombosis
…, S Middeldorp, JCM Meijers, S Zeerleder - … , and vascular biology, 2013 - Am Heart Assoc
Objective— The formation of neutrophil extracellular traps and the exposure of nucleosomes
on these neutrophil extracellular traps contribute to coagulation activation and the …
on these neutrophil extracellular traps contribute to coagulation activation and the …
[HTML][HTML] Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation
In inflammation, extensive cell death may occur, which results in the release of chromatin
components into the extracellular environment. Individually, the purified chromatin components …
components into the extracellular environment. Individually, the purified chromatin components …
DAMP and DIC: the role of extracellular DNA and DNA-binding proteins in the pathogenesis of DIC
Disseminated intravascular coagulation (DIC) is a heterogeneous group of disorders, which
manifest as a spectrum of haemorrhage and thrombosis complicating many primary …
manifest as a spectrum of haemorrhage and thrombosis complicating many primary …
Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients
…, FCJI Heubel-Moenen, E Nur, SS Zeerleder… - Science translational …, 2020 - science.org
Disruption of the intestinal microbiota occurs frequently in allogeneic hematopoietic cell
transplantation (allo-HCT) recipients and predisposes them to development of graft-versus-host …
transplantation (allo-HCT) recipients and predisposes them to development of graft-versus-host …
C1-inhibitor: more than a serine protease inhibitor
S Zeerleder - Seminars in thrombosis and hemostasis, 2011 - thieme-connect.com
C1-inhibitor (C1-inh) is a crucial regulator of the activation of plasmatic cascade systems
involved in inflammation contributing to the homeostasis in the generation of proinflammatory …
involved in inflammation contributing to the homeostasis in the generation of proinflammatory …
Mechanisms of haemolysis-induced kidney injury
K Van Avondt, E Nur, S Zeerleder - Nature Reviews Nephrology, 2019 - nature.com
Intravascular haemolysis is a fundamental feature of chronic hereditary and acquired
haemolytic anaemias, including those associated with haemoglobinopathies, complement …
haemolytic anaemias, including those associated with haemoglobinopathies, complement …