In this review, we discuss recent developments in the field of nanoparticles and their use in
tissue regeneration approaches. Owing to their unique chemical properties and flexibility in …

Nanoparticles allow for controlled and targeted drug delivery to diseased tissues and therefore
bypass systemic side effects. Spatiotemporal control of drug release can be achieved by …

The role that biomaterials play in the clinical treatment of damaged organs and tissues is
changing. While biomaterials used in permanent medical devices were required to passively …

This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry
as many new approaches to the design of innovative metal-based anticancer drugs are …

Cigarette smoke mediates DNA damage, lipid peroxidation, and modification and misfolding
of proteins, thereby inducing severe cellular damage. The ubiquitin proteasome system …

Respiratory diseases are an increasing burden for the ageing population. Although our
understanding of these diseases has improved significantly over the past decades, diagnostic …

The cytotoxicity, hydrophobicity (log P), cellular uptake, aqueous reactivity, and extent of
DNA adduct formation in the A2780 ovarian carcinoma cells for four osmium(II) arene …

Iodido osmium(II) complexes [Os(η 6 -arene)(XY)I] + (XY = p-hydroxy or p-dimethylaminophenylazopyridine,
arene = p-cymene or biphenyl) are potently cytotoxic at nanomolar …

Chlorido osmium(II) arene [(η 6 -biphenyl)Os II (X-pico)Cl] complexes containing X = Br (1),
OH (2), and Me (3) as ortho, or X = Cl (4), CO 2 H (5), and Me (6) as para substituents on the …

We show that the binding mode adopted by picolinamide derivatives in organometallic Os II
and Ru II half-sandwich complexes can lead to contrasting cancer cell cytotoxicity. N-Phenyl …