User profiles for SL Johnston

Sebastian L Johnston

Professor of Respiratory Medicine & Allergy, Imperial College London
Verified email at imperial.ac.uk
Cited by 72699

Allergic rhinitis and its impact on asthma (ARIA) 2008

…, L Grouse, M Humbert, C Jackson, SL Johnston… - Allergy, 2008 - Wiley Online Library
Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

Takayasu arteritis: a review

SL Johnston, RJ Lock, MM Gompels - Journal of clinical pathology, 2002 - jcp.bmj.com
Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details
the history, clinical features, differential diagnoses, classification, and immunology of the …

Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease

…, D Clarke, M Birrell, M Belvisi, SL Johnston - Pharmacology & …, 2009 - Elsevier
Asthma and chronic obstructive pulmonary disease are inflammatory lung disorders
responsible for significant morbidity and mortality worldwide. While the importance of allergic …

Community study of role of viral infections in exacerbations of asthma in 9-11 year old children

SL Johnston, PK Pattemore, G Sanderson, S Smith… - Bmj, 1995 - bmj.com
Objective: To study the association between upper and lower respiratory viral infections and
acute exacerbations of asthma in schoolchildren in the community. Design: Community …

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

PAB Wark, SL Johnston, F Bucchieri, R Powell… - The Journal of …, 2005 - rupress.org
Rhinoviruses are the major trigger of acute asthma exacerbations and asthmatic subjects
are more susceptible to these infections. To investigate the underlying mechanisms of this …

Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations

…, G Caramori, LM Fabbri, SL Johnston - American journal of …, 2006 - atsjournals.org
Rationale: Severe exacerbations of chronic obstructive pulmonary disease (COPD) are
major causes of health care costs mostly related to hospitalization. The role of infections in …

Role of deficient type III interferon-λ production in asthma exacerbations

…, DE Davies, SV Kotenko, A Papi, SL Johnston - Nature medicine, 2006 - nature.com
Rhinoviruses are the major cause of asthma exacerbations, and asthmatics have increased
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …

Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease

…, TW Meade, DJ Jeffries, SL Johnston… - American journal of …, 2001 - atsjournals.org
The effects of respiratory viral infection on the time course of chronic obstructive pulmonary
disease (COPD) exacerbation were examined by monitoring changes in systemic …

Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers

…, DA Lomas, MR Barer, SL Johnston… - American journal of …, 2011 - atsjournals.org
… Papi A, Bellettato CM, Braccioni F, Romagnoli M, Casolari P, Caramori G, Fabbri LM, Johnston
SL. Infections and airway inflammation in chronic obstructive pulmonary disease severe …

Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study

…, J Schreiber, G Sanderson, ST Holgate, SL Johnston - The Lancet, 2002 - thelancet.com
Johnston SLJohnston SL … Sebastian L Johnston initiated the study and contributed
to its design, RT-PCR, data analysis, and drafting the article. …